The Q226L mutation can convert a highly pathogenic H5 2.3.4.4e virus to bind human-type receptors.

H5Nx viruses continue to wreak havoc in avian and mammalian species worldwide. The virus distinguishes itself by the ability to replicate to high titers and transmit efficiently in a wide variety of hosts in diverse climatic environments. Fortunately, transmission to and between humans is scarce.

Opposite asymmetry in visual perception of humans and macaques.

In human adults, visual perception varies throughout the visual field. Performance decreases with eccentricity and varies around polar angle. At isoeccentric locations, performance is typically higher along the horizontal than vertical meridian (horizontal-vertical asymmetry [HVA]) and along the lower than the upper vertical meridian (vertical meridian asymmetry [VMA]).

Asymmetries in foveal vision.

Visual perception is characterized by known asymmetries in the visual field; human's visual sensitivity is higher along the horizontal than the vertical meridian, and along the lower than the upper vertical meridian. These asymmetries decrease with decreasing eccentricity from the periphery to the center of gaze, suggesting that they may be absent in the 1-deg foveola, the retinal region used to explore scenes at high-resolution. Using high-precision eyetracking and gaze-contingent display, allowing for accurate control over the stimulated foveolar location despite the continuous eye motion at fixation, we investigated fine visual discrimination at different isoeccentric locations across the foveola and parafovea.