Publications by authors named "M Arif M Jamali"

Background: Infectious diseases remain the leading cause of death among children younger than 5 years due to disparities in access and acceptance of essential interventions. The Community Mobilisation and Community Incentivisation (CoMIC) trial was designed to evaluate a customised community mobilisation and incentivisation strategy for improving coverage of evidence-based interventions for child health in Pakistan.

Methods: CoMIC was a three-arm cluster-randomised, controlled trial in rural areas of Pakistan.

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Heart transplantation is a vital procedure for patients with end-stage heart failure, but it faces significant challenges, including graft dysfunction, rejection, and cardiac allograft vasculopathy (CAV), which can compromise long-term graft success. Research suggests that statin therapy may offer significant benefits to heart transplant recipients, such as improved long-term survival and reduced rates of graft rejection and mortality. The aim of this review is to thoroughly examine the recent literature on this topic since 2005.

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  • - The study reviews the relationship between vitamin D serum levels and diabetic foot ulcers (DFU), noting that DFU patients generally have significantly lower vitamin D levels compared to those with diabetes without DFU.
  • - Eight meta-analyses were analyzed, indicating that severe vitamin D deficiency increases the risk of developing DFU by at least 1.82 times and that vitamin D supplementation may improve ulcer outcomes.
  • - The findings suggest a potential benefit of vitamin D for DFU patients, but the reliability of the data is questioned due to possible biases in the studies examined.
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  • Muscular dystrophy (MD) is a genetic disorder characterized by muscle weakness, with a higher prevalence in regions like Iran due to common consanguineous marriages.
  • The study focused on three unrelated families with undiagnosed cases of MD and used whole exome sequencing (WES) to identify mutations in genes associated with collagen type VI.
  • The findings revealed specific mutations in the COL6A genes for each family, highlighting WES as a useful tool for diagnosing unidentified MD cases and expanding knowledge about its genetic causes in Iran.
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Approximately five billion people do not have access to necessary surgical treatment globally and up to 85% of children in LMICs are affected with conditions requiring surgical care by the age of 15 years. It is crucial to identify common surgical conditions in children in Pakistan to inform healthcare professionals and policymakers for effective resource allocation. This representative cross-sectional household survey conducted on children aged 5-10 years assessed existing surgical diseases and healthcare-seeking behaviors in the two largest provinces (Sindh and Punjab) of Pakistan.

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