Publications by authors named "M Arazi"
Objective: To investigate the outcomes of primary enucleation and adjuvant systemic chemotherapy, when deemed appropriate, on a cohort of children with unilateral intraocular Rb (AJCC 8th edition, cT2 and cT3) from diverse economic groupings.
Methods: A prospective analysis including treatment-naïve Rb patients were presented to 11 centers from 10 countries from January 1 to December 31, 2019, and were followed-up thereafter. Only children with unilateral intraocular Rb that underwent primary enucleation were included in the present analysis.
Article Synopsis
- This study compares the outcomes and characteristics of frontal sling surgery for correcting ptosis in pediatric versus adult patients.
- The research included 62 patients, revealing that simple congenital ptosis was most common in children, while adults often had myogenic ptosis related to systemic conditions.
- The results indicated significant differences in pre-operative measurements and complications, with adults showing higher rates of issues like sling extrusion and a correlation between previous surgeries and postoperative complications.
Article Synopsis
- This study aims to examine the histopathology and outcomes in patients with retinoblastoma who underwent eye enucleation and had neovascular glaucoma (NVG).
- The research included 1,420 total cases from five continents, revealing that 16% of patients with NVG were often at higher risk of severe histopathological findings.
- The findings indicate that NVG is linked to more aggressive forms of the disease and a higher chance of metastasis, emphasizing the need for careful monitoring and treatment in these cases.
Purpose: To compare the clinical outcomes of children with unilateral retinoblastoma (Rb) and high-risk histopathology features (HRHF) following upfront enucleation with/without adjuvant chemotherapy, and investigate cases locally considered non-HRHF but converted to a standardized HRHF definition.
Design: Retrospective multinational clinical cohort study.
Methods: Children with Rb who presented to 21 centers from 12 countries between 2011-2020, and underwent primary enucleation were recruited.
Article Synopsis
- The study investigates the risk factors for needing a second surgery in patients with congenital ptosis, highlighting the added morbidity associated with reoperation.
- Conducted retrospectively, the research looked at patients who had their first ptosis correction surgery at Sheba Medical Center from 2012 to 2021, noting demographic and surgical details.
- Results indicate that younger males have a significantly higher risk for reoperation, and that older age seems to provide some protection against needing a second procedure.