Objectives: Corallium rubrum, the precious red coral, is an octocoral endemic to the western Mediterranean Sea. Like most octocorals, it produces tiny, calcified structures called sclerites. Uniquely, it also produces a completely calcified axial skeleton that is a bright red color.
View Article and Find Full Text PDFThe search and identification of inhibitory molecules from novel natural sources, such as pisco grape pomace extract obtained by green techniques, may help to develop agents with therapeutic potential that are beneficial to health with fewer adverse effects than drugs. Many drugs act as enzyme inhibitors, decreasing their activity and thus correcting a metabolic imbalance. This study aims to identify bioactive molecules with antioxidant and inhibitory activity over acetylcholinesterase and cyclooxygenase enzymes present in pisco grape pomace green extracts.
View Article and Find Full Text PDFPolycyclic aromatic hydrocarbons (PAH) are semi-volatile, lipophilic, and harmful compounds that can persist for decades in a range of marine environments. There are several marine and soil microorganisms that possess enzymes involved in arene degradation. Here, we analyzed the structure (16S rRNA amplicons) and metabolic potential (inferred using phylogenetic placement) of the bacterial community in surface marine sediments from coastal waters off Concepción, Chile, and describe how microbial community patterns are shaped and altered by PAH contamination.
View Article and Find Full Text PDFJ Intensive Care Med
November 2024
This narrative review explores the implementation and impact of sepsis code protocols, an urgent intervention strategy designed to improve clinical outcomes in patients with sepsis. We examined the degree of implementation, activation criteria, areas of implementation, personnel involved, responses after activation, goals and targets, impact on clinical indicators, and challenges in implementation. The reviewed evidence suggests that sepsis codes can significantly reduce sepsis-related mortality and enhance early administration of treatments.
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