Cognitive functioning in young people with first episode psychosis: relationship to diagnosis and clinical characteristics.

Objective: To examine the extent and nature of neuropsychological deficits in adolescents and young people with first episode psychosis (FEP), and to determine whether the pattern and extent of neuropsychological deficits varied according to diagnosis.

Method: A total of 83 FEP subjects aged 13-25 years, and 31 healthy controls completed a comprehensive battery of neuropsychological tests, grouped into 10 cognitive domains. First episode psychosis subjects were stratified into three diagnostic groups (schizophrenia, affective disorders, substance-induced psychosis) and differences in cognitive profiles were examined.

Memory function in childhood epilepsy syndromes.

Objective: Children with epilepsy are at risk of specific cognitive deficits. We aimed to compare and characterize the memory function of children with childhood absence epilepsy (CAE), frontal lobe epilepsy (FLE) and temporal lobe epilepsy (TLE).

Methods: Epilepsy syndrome was identified by clinical data, seizure semiology, interictal and ictal electroencephalogram (EEG).

Lateralized-temporal-lobe-lesion effects on learning and memory: examining the contributions of stimulus novelty and presentation mode.

Previous studies have attributed poor memory for words after left temporal lobectomy (LTL) to a verbal memory deficit and poor memory for abstract designs after right temporal lobectomy (RTL) to a difficulty in remembering nonverbal/visual stimuli. In this investigation, the contribution of stimulus novelty to lateralised-lesion-effects was evaluated by testing list learning in 11 LTL, 8 RTL and 14 normal control subjects, using four types of material (familiar verbal, novel verbal, familiar designs and novel designs). In addition, the effect of presentation modality (spoken vs.

Intelligence in childhood epilepsy syndromes.

Unlabelled: Intellectual deficits play a significant role in the psychosocial comorbidity of children with epilepsy. Early educational intervention is critical.

Objective: This study aims to determine the intellectual ability of children with common childhood epilepsy syndromes-generalised idiopathic epilepsy (GIE), generalised symptomatic epilepsy (GSE), temporal lobe epilepsy (TLE), frontal lobe epilepsy (FLE), central epilepsy (CE) and non-localised partial epilepsy (PE).