Publications by authors named "M Antila"
Objective: This paper aims to review the efficacy and safety of current chronic urticaria (CU) treatment in children and the existing patient-reported outcome measures (PROMs) used in this age group.
Data Source: Since there are few studies of CU in children, the authors performed a non-systematic review of published articles in English, Spanish, and Portuguese in the PubMed database in the last decade. Keywords used were (antihistamines OR omalizumab OR cyclosporine OR treatment) AND (chronic urticaria) AND (children OR adolescents).
Background: In phase 3 VOYAGE (NCT02948959; Evaluation of Dupilumab in Children With Uncontrolled Asthma), dupilumab showed clinical efficacy with an acceptable safety profile in children aged 6 to 11 years with uncontrolled moderate to severe type 2 asthma (blood eosinophils ≥150 cells/μL or FeNO ≥20 ppb).
Objective: We analyzed dupilumab's efficacy in children with type 2 asthma by high- or medium-dose inhaled corticosteroids (ICS) at baseline.
Methods: Children were randomized to receive add-on dupilumab 100/200 mg (by body weight ≤30 kg/>30 kg) every 2 weeks or placebo for 52 weeks and stratified by high- or medium-dose ICS at baseline.
Article Synopsis
- Sleep plays a significant role in regulating emotions, but its specific contributions, particularly concerning physiological responses to stress, are not well understood.
- A study involving Finnish participants explored the effects of suppressing specific sleep stages (REM and slow-wave sleep) on stress responses and memory, finding that suppressing slow-wave sleep resulted in a greater physiological stress response.
- The research suggests that REM sleep, specifically its theta brain activity, helps consolidate emotional responses, while the dependence of declarative memory consolidation on sleep stages is less clear.
Objective: To assess prescription patterns for short-acting b2 agonists (SABAs) and other asthma medications in asthma patients treated by specialists and participating in the SABA use IN Asthma (SABINA) study in Brazil.
Methods: This was an observational, cross-sectional study conducted at five sites in different regions of Brazil. The primary endpoints were to record SABA prescriptions and obtain data on over-the-counter (OTC) SABA purchases at the pharmacy.
Wind power is one of the fastest growing renewable energy sectors and plays a focal role in the transition to a fossil fuel free society in Europe. Technological developments have enabled the construction of turbines within forested areas, which has raised concerns regarding the audio-visual impact on these landscapes. However, there is a paucity of research with regard to the role that forests may play in mitigating the negative impacts of wind farms.
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