Significant attenuation of fully automated thrombin generation in newly diagnosed multiple myeloma patients after induction therapy.

Nearly 10% of newly diagnosed multiple myeloma (NDMM) patients develop a venous thromboembolism (VTE) episode during their disease course, despite current thromboprophylaxis strategies. Changes in hypercoagulability in these patients after treatment have been analyzed using the thrombin generation (TG) assay, the results being discrepant, probably due to the use of semi-automated techniques. This study aims to assess changes in TG measured by a fully automated analyzer.

Standardized body condition scoring system for tropical farm animals (large ruminants, small ruminants, and equines).

In tropical regions, subject to significant fluctuations in feedstuffs, the body condition score (BCS) is a relevant indicator for monitoring body reserves status of farm animals. However, the most used BCS grids comes from temperate conditions and still not adapted for tropical species, which limits adoption and usefulness. The current work presents for the first time an original, low-cost, standardized BCS assessment system, suited to a large spectrum of tropical farm animals (zebu and/or crossbred cattle, buffaloes, camel, sheep, goats, horses and donkeys).

Heart Rate response and cardiovascular risk during OSA: an easy biomarker derived from pulse oximetry.

Background: Sleep apnoea specific heart rate response (ΔHR) has been identified as a promising biomarker for stratifying cardiovascular (CV) risk, and predicting positive airway pressure (PAP) benefit in obstructive sleep apnoea (OSA). However, the need for prior manual scoring of respiratory events potentially limits the accessibility and reproducibility of ΔHR. We aimed to evaluate the association of pulse rate response to oxygen desaturations automatically derived from pulse oximetry (ΔHR) with CV risk in OSA.

[Vitiligo and alopecia areata in children : the dermatologist's perspective].

Vitiligo and alopecia areata are chronic autoimmune dermatoses that are relatively common in the pediatric population. Vitiligo is a pigmentation disorder and alopecia areata is a non-scarring alopecia. Both conditions can be highly stigmatizing and have a significant impact on the mental health and quality of life of young patients and their families.

Accelerating veterinary low field MRI acquisitions using the deep learning based denoising solution HawkAI.

Magnetic resonance imaging (MRI) has changed veterinary diagnosis but its long-sequence time can be problematic, especially because animals need to be sedated during the exam. Unfortunately, shorter scan times implies a fall in overall image quality and diagnosis reliability. Therefore, we developed a Generative Adversarial Net-based denoising algorithm called HawkAI.