Atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion: cytohistologic correlation study with diagnostic pitfalls.

Objective: In the current study, we explore the diagnostic parameters and pitfalls in the follow-up of 123 cases of Pap smears diagnosed as high-grade atypical squamous cells (ASC-H) at our institution.

Study Design: A computer database search was performed from the archives of the Ottawa Hospital Cytopathology Service for cases diagnosed with ASC-H between January 2003 and July 2005.

Results: Follow-up of the 123 cases of ASC-H showed high grade squamous intraepithelial lesion (HSIL) in 73 patients (59.

Fine needle aspiration biopsy of hepatocellular carcinoma. Value of immunocytochemical and ultrastructural studies.

Over three years, 365 fine needle aspiration biopsies (FNABs) of the liver were performed at Ottawa Civic Hospital. Fifty-nine percent of these aspirates were positive for malignancy. A diagnosis of hepatocellular carcinoma (HCC) was made in 20 liver aspirates.