Publications by authors named "M Andreansky"

Article Synopsis
  • G-CSF after hematopoietic stem cell transplantation (HSCT) improves neutrophil recovery in neutropenic patients, but its safety in sickle cell disease (SCD) patients was previously unknown.
  • Clinical outcomes were studied in 62 SCD patients receiving G-CSF post-HSCT, showing effective neutrophil and platelet engraftment without any SCD-related complications.
  • Common post-treatment issues included anorexia, hypertension, and electrolyte imbalances, but overall, G-CSF was determined to be safe for SCD patients following HSCT.
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The first cases of COVID-19 were initially recorded in December 2019 in Wuhan, the capital of China's Hubei Province. The situation quickly escalated and turned into a global pandemic. COVID-19 is a highly infectious respiratory disease that leads to decreased respiratory, physical, and psychological function of affected patients (2).

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Hematopoietic stem cell transplantation (HSCT) is a therapeutic option for many nonmalignant disorders (NMD) and is curative or prevents disease progression. Reduced-intensity conditioning (RIC) in HSCT for NMD may reduce regimen-related acute toxicities and late complications. Myeloablation is often replaced by immune suppression in RIC regimens to support donor engraftment.

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Allogeneic hematopoietic stem cell transplantation (HSCT) can cure transfusion-dependent thalassemia (TDT). In a multicenter trial we investigated the efficacy of reduced-intensity conditioning (RIC) before unrelated donor (URD) HSCT in children with TDT. Thirty-three children, ages 1 to 17 years, received bone marrow (BM) or umbilical cord blood (UCB) allografts.

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