Publications by authors named "M Andert"
Article Synopsis
- Central nervous system (CNS) cells, like microglia and astrocytes, play critical roles in the development and progression of multiple sclerosis (MS) through their inflammatory responses.
- Recent findings show that these cells not only promote inflammation but can also help resolve it, highlighting their complexity and protective functions.
- Heparin-binding EGF-like growth factor (HB-EGF) is identified as a key player in providing anti-inflammatory and protective effects during MS, with potential therapeutic implications, especially when administered intranasally in preclinical studies.
Distinct forebrain regions define a dichotomous astrocytic profile in multiple system atrophy.
Acta Neuropathol Commun
January 2024
The growing recognition of a dichotomous role of astrocytes in neurodegenerative processes has heightened the need for unraveling distinct astrocytic subtypes in neurological disorders. In multiple system atrophy (MSA), a rare, rapidly progressing atypical Parkinsonian disease characterized by increased astrocyte reactivity. However the specific contribution of astrocyte subtypes to neuropathology remains elusive.
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