Publications by authors named "M Anderegg"
Article Synopsis
- A study investigated the effectiveness of empagliflozin, a sodium-glucose cotransporter 2 inhibitor, in preventing kidney stones in nondiabetic adults with a history of calcium or uric acid stones.
- The trial involved 53 participants who were given either empagliflozin or a placebo in a crossover design, focusing on changes in urine supersaturation ratios relevant to stone recurrence.
- Results showed significant reductions in urine supersaturation ratios for calcium phosphate in calcium stone formers and uric acid in uric acid stone formers, indicating that empagliflozin may help prevent certain types of kidney stones without serious side effects.
Unsupervised Feature Extraction From Raw Data for Gesture Recognition With Wearable Ultralow-Power Ultrasound.
IEEE Trans Ultrason Ferroelectr Freq Control
July 2024
Wearable ultrasound (US) is a novel sensing approach that shows promise in multiple application domains, and specifically in hand gesture recognition (HGR). In fact, US enables to collect information from deep musculoskeletal structures at high spatiotemporal resolution and high signal-to-noise ratio, making it a perfect candidate to complement surface electromyography for improved accuracy performance and on-the-edge classification. However, existing wearable solutions for US-based gesture recognition are not sufficiently low power for continuous, long-term operation.
View Article and Find Full Text PDFThiazide and thiazide-like diuretics (thiazides) belong to the most frequently prescribed drugs worldwide. By virtue of their natriuretic and vasodilating properties, thiazides effectively lower blood pressure and prevent adverse cardiovascular outcomes. In addition, through their unique characteristic of reducing urine calcium, thiazides are also widely employed for the prevention of kidney stone recurrence and reduction of bone fracture risk.
View Article and Find Full Text PDFPrevalence and characteristics of genetic disease in adult kidney stone formers.
Nephrol Dial Transplant
August 2024
Article Synopsis
- - The study aimed to investigate the genetic factors involved in kidney stone formation among adults, particularly those with a history of kidney stones, by analyzing the genetic makeup of participants from the Bern Kidney Stone Registry.
- - Whole exome sequencing revealed that 2.9% of kidney stone formers had identifiable Mendelian kidney stone diseases, with cystinuria being the most common, while 8.1% had variants associated with nephrolithiasis.
- - Findings indicated that individuals with Mendelian kidney stone diseases experienced their first stone event at a younger age and exhibited different stone compositions compared to those without genetic diagnoses, highlighting the complexity of genetic contributions to nephrolithiasis.