Clinical feasibility of pulmonary perfusion analysis using dynamic computed tomography and a gamma residue function.

Purpose: To create and determine the clinical feasibility of a model based on dynamic computed tomography (CT) and a bolus injection of iodine contrast medium for evaluation of pulmonary perfusion for healthy individuals and for patients with lung diseases.

Materials And Methods: We analyzed pulmonary perfusion by means of dynamic 16-row multidetector CT scanning with a gamma residue function with adding a linear component (extended gamma function model) for 20 healthy individuals and in five patients.

Results: Four types of the time-attenuation curve (TAC) were identified for the peripheral lung.

Cytoskeletal involvement in hypothermic renal preservation injury.

Background: Cytoskeletal degradation occurs in warm renal ischemia and reperfusion and during hypothermia. The purpose of this study was to determine cytoskeletal changes during cold storage preservation injury in renal tubules and to determine whether these changes contribute to the injury.

Methods: Isolated canine renal proximal tubules or their primary epithelial cultures were cold-stored in University of Wisconsin solution and reperfused in vitro to simulate renal cold storage preservation injury.

Role of peroxynitrite anion in renal hypothermic preservation injury.

Background: Peroxynitrite anions may play a role in normothermic renal ischemia and reperfusion. The purpose of this study was to determine if endogenous peroxynitrite anion is involved in renal preservation injury.

Methods: Experiments were conducted in isolated canine renal tubules and in a canine autotransplant model of hypothermic preservation injury.

Pallidoreticular damage in acute carbon monoxide poisoning: diffusion-weighted MR imaging findings.

We describe a case of carbon monoxide poisoning that led to pallidoreticular damage and delayed leukoencephalopathy. Serial diffusion-weighted MR imaging was performed. A restricted water diffusion pattern was demonstrated in the globus pallidus and substantia nigra in the early stage.

Intravascular malignant lymphomatosis: diffusion-weighted magnetic resonance imaging characteristics.

Intravascular malignant lymphomatosis is an unusual condition in which malignant lymphoma cells form microscopic masses within the blood vessels of the central nervous system. Occlusion of the involved blood vessels can lead to multifocal cerebral infarcts. Diffusion-weighted magnetic resonance imaging (MRI) reveals a subacute infarction pattern (bright high signal intensity on b = 1000 s/mm2 images and intermediate apparent diffusion coefficient values) in the cerebral deep white matter.