Publications by authors named "M Amanzio"

Alongside rapid population ageing, we are experiencing increasing numbers of people with cognitive impairment and dementia. There is great scientific effort being committed to understanding cognitive and brain functioning, with the aim of helping to promote healthy ageing and independence, and improve quality of life. This Cognitive Ageing Collection brings together cutting-edge research using a variety of methods and from diverse disciplinary perspectives, with example topics including cognitive strategies, genetic risk factors, and emotion regulation.

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The response of older people to the COVID-19 pandemic has attracted much attention as they are at increased risk of adverse outcomes. A longitudinal study has shown that improvement in global cognitive, executive and language functioning in healthy older adults enrolled at the University of the Third Age appears to play a protective role against emotional dysregulation and mood changes during the pandemic. To date, no study has examined emotional dysregulation through COVID-19-related images using facial electromyographic recordings in healthy older adults.

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Article Synopsis
  • This study investigates the impact of placebo analgesia (pain relief) and nocebo hyperalgesia (pain increase) in patients with mild-to-moderate Alzheimer's disease (AD), which is not well understood.
  • Twenty-one AD patients and 26 healthy participants were exposed to thermal pain under different conditions involving lidocaine and capsaicin, with verbal suggestions to influence pain perception.
  • Results showed that healthy participants experienced placebo effects, while AD patients did not show significant placebo or nocebo effects, suggesting that AD might limit these phenomena, which is important for clinical trial design and treatment approaches.
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Mental flexibility (MF) has long been defined as cognitive flexibility. Specifically, it has been mainly studied within the executive functions domain. However, there has recently been increased attention towards its affective and physiological aspects.

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