Cell populations in the pineal gland of the viscacha (Lagostomus maximus). Seasonal variations.

Pineal samples of the viscacha, which were taken in winter and in summer, were analysed using both light and electron microscopy. The differences found between the two seasons were few in number but significant. The parenchyma showed two main cell populations.

Age-related morphometric changes in the pineal gland. A comparative study between C57BL/6J and CBA mice.

Relatively little is known about the effects of melatonin on the aging of the pineal, the organ which is the main place for synthesis of this hormone. Using simple morphometric methods, some parameters of the pineal gland, such as total volume, number of pinealocytes and pinealocyte volume were estimated in two mice strains: normal CBA and melatonin-deficient C57BL/6J. Two age groups, 6 weeks and 10 months, were studied in order to evaluate possible differential age-related changes between both strains.

Size and degeneration increase in herring bodies during aging in hamsters.

The hypothalamo-neurohypophysial tract of young, adult and aged male hamsters was studied at lateral and ventral regions of hypothalamus by means of electron microscopy. Neurosecretory swelling axons (Herring bodies) were usually found as classically described containing abundant neurosecretory granules, mitochondria, few microtubules and profiles of smooth endoplasmic reticulum in all groups of age. However, in aged hamsters, starting at 18-month-old subjects, we observed that the size of some neurosecretory axons was highly increased.

Quantitative ultrastructural evidences suggest no age-related changes in biosynthesis and processing within parvocellular cells of the paraventricular nucleus in hamsters.

The parvocellular neurons of the parvocellular division of the paraventricular nucleus (PVPA) were studied in hamsters at six point ages (from 3 to 30 months old). Standard manual morphometric techniques were used to obtain data of parvocellular activity including nuclear and nucleolar size, as well as the percentage of the cell occupied by Golgi apparatus (GA), mitochondria and rough endoplasmic reticulum (RER). Other directly age-related parameters like amounts of nuclear invagination and lipofuscin have also been studied.

The magnocellular neurosecretory system of the hamster hypothalamus: an ultrastructural and morphometric study during lifetime.

A quantitative study regarding the age-related changes occurring in the nucleus and the somatic organelles of neurosecretory magnocellular neurons of the hypothalamo neurohypophyseal system (HNS) was carried out in the hamster at six age-points during animal life. The magnocellular cells of both parts of the supraoptic nucleus (SON) and the paraventricular nucleus (PVN) of male Syrian hamsters between 3 and 30 months of age were examined ultrastructurally. Cells of all age groups present the same morphological ultrastructure.