Publications by authors named "M Alshorman"
Article Synopsis
- The study focuses on the need for new prognostic markers and treatment targets in the diverse landscape of breast cancer, using the METABRIC dataset to analyze gene expression.
- It found that higher levels of PD-L1 and MET genes are linked to poorer tumor characteristics and are more prevalent in certain aggressive breast cancer subtypes.
- The research suggests that targeting both PD-L1 and MET may be beneficial, especially for patients with tumors showing high levels of these proteins, even though their expression did not directly correlate with overall survival rates.
A new formulation of hydrogel dosimeter consisting of ferrous-methylthymol blue (MTB)-polyvinyl alcohol (PVA) cross-linked chemically with glutaraldehyde (GTA) was studied and evaluated by nuclear magnetic resonance analysis by means of the R spin-spin relaxation rate. Previous optical studies of this transparent solid chemically cross-linked gel showed important dosimetric features in terms of sensitivity, auto-oxidation rate, and diffusion. This study shows that the MTB-PVA-GTA dosimeter has a reproducible linear dose response up to 40 Gy.
View Article and Find Full Text PDFHigh-energy x-ray diffractometer for nondestructive strain depth profile measurement.
Rev Sci Instrum
December 2013
We describe a lab-based high-energy x-ray diffraction system and a new approach to nondestructively measuring strain profiles in polycrystalline samples. This technique utilizes the tungsten K(α1) characteristic radiation from a standard industrial x-ray tube. We introduce a simulation model that is used to determine strain values from data collected with this system.
View Article and Find Full Text PDFBackground: A new approach for evaluating the optical penetration depth and testing its validity with Monte Carlo simulations and Kubelka-Munk theory is used for artificial semi-rigid tissue sensitized with natural pigments. Photodynamic therapy is a promising cancer treatment in which a photosensitizing drug concentrates in malignant cells and is activated by visible light at certain wavelength.
Materials And Methods: Cheap artificial semi-rigid tissue incorporated with scattering and absorbing materials along with some other composites comparable to normal human tissue has been performed.