Introduction: Numerous epidemiological studies have demonstrated that consuming foods rich in polyphenols and flavonoids can have beneficial effects on various diseases, including arterial hypertension (HTN). Recent research from our laboratory has shown that certain flavonoids exhibit antihypertensive properties in several animal models of HTN. Our objective was to evaluate the effect of L.
View Article and Find Full Text PDFCellular biomaterials offer unique properties for diverse biomedical applications. However, their complex viscoelastic behavior requires careful consideration for design optimization. This study explores the effective viscoelastic response of two promising unit cell designs (tetrahedron-based and octet-truss) suitable for high porosity and strong mechanics.
View Article and Find Full Text PDFThis study investigated postharvest dopamine treatment efficiency in ameliorating chilling injury of banana fruits during storage at 7 ºC for 21 days. Our results showed that dopamine treatment at 150 µM promoted phenols and flavonoids biosynthesis acquired by higher phenylalanine ammonia-lyase (PAL) expression and activity concurrent with lower polyphenol oxidase (PPO) expression and activity leading to higher DPPH, FRAP, and ABTS radicals scavenging activity. In addition, dopamine treatment at 150 µM promoted endogenous proline biosynthesis by activating pyrroline-5-carboxylate synthetase (P5CS) and ornithine δ-aminotransferase (OAT) expression and activity concurrent with suppressing proline dehydrogenase (ProDH) expression and activity.
View Article and Find Full Text PDFBackground: This paper presents a novel approach to predict and map radon and thoron levels. We developed separate radon and thoron prediction maps for Ireland and introduced a system for producing high-resolution 3D radiation maps which may be used for planning purposes in residential areas, recycling and demolishing waste depots, and quarries of building and construction material. Additionally, we highlight the critical need to monitor thoron alongside radon in indoor surveys, as thoron's shorter half-life and higher energy levels may pose a greater health risk.
View Article and Find Full Text PDFThis paper presents novel configurations for additively manufactured lattice structures, including helical and elliptic designs, in addition to the pyramid base model. Functionally graded versions of the pyramid and elliptic lattice structures are developed by considering desirable relative densities in each layer. The lattice structures were manufactured using Ti-6Al-4V powder in a three-dimensional selective laser melting printer.
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