Publications by authors named "M Alevizaki"
A cohort of radioiodine-refractory differentiated thyroid cancer patients (RAI-R DTC) in a tertiary center underwent therapeutic interventions according to disease progression rate and metastasis location. We evaluated the independent impact of local and/or systemic treatments on final outcomes in 122 RAI-R DTC patients (44.3% men, age at diagnosis 51.
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- An online survey of European thyroid specialists revealed that 28% believe thyroid hormone (TH) treatment may be appropriate for euthyroid patients with growing simple goiters, despite guidelines against this practice.
- There were significant regional differences in support for TH treatment, with only 7% in The Netherlands compared to 78% in the Czech Republic.
- Factors influencing the likelihood of recommending TH included the specialist's age and the historical iodine insufficiency of their region, while gender, country, and economic factors showed weak associations.
Treatment of Obesity with Thyroid hormones in Europe. Data from the THESIS* Collaboration.
J Endocrinol Invest
January 2025
Purpose: The use of thyroid hormones (TH) to treat obesity is unsupported by evidence as reflected in international guidelines. We explored views about this practice, and associations with respondent characteristics among European thyroid specialists.
Methods: Specialists from 28 countries were invited to a survey via professional organisations.
Article Synopsis
- - The study aimed to assess how European thyroid specialists view levothyroxine (LT4) treatment for euthyroid women with positive thyroid peroxidase antibodies (TPOAb) to improve fertility, as current evidence does not support this practice.
- - An international survey (THESIS) revealed that 42.8% of over 2,316 respondents believe LT4 might be indicated for these patients, with significant variation across countries, highlighting a range from 22.9% to 83.7% of positive responses.
- - Factors such as gender, age, and clinical experience influenced opinions; younger specialists and those who treat more thyroid patients were more likely to consider LT4, raising concerns about potential overtreatment risks in
Two rare cases of benign struma ovarii with malignant recurrence.
Endocrinol Diabetes Metab Case Rep
April 2024
Article Synopsis
- - Struma ovarii is a type of ovarian teratoma found in 2-5% of cases, and malignant transformation is rare (<5%), with two cases presented where benign struma ovarii evolved into highly differentiated follicular carcinoma of the ovary (HDFCO) years later.
- - The first case involved a 37-year-old woman who had multiple metastases after being previously diagnosed with benign struma ovarii 14 years ago, while the second case was a 26-year-old woman whose condition re-emerged 4 years after a benign diagnosis.
- - Both patients underwent surgery along with total thyroidectomy and radioactive iodine therapy, highlighting the challenges in diagnosing HDFCO due to its histological similarities