Comparative Assessment of the Influence of Various Time Intervals upon the Linear Accuracy of Regular, Scannable, and Transparent Vinyl Polysiloxane-Based Bite Registration Materials for Indirect Dental Restoration Fabrication.

Interocclusal records (IORs) created with bite registration materials (BRMs) accurately reflect the opposing teeth's physiological and anatomical associations in digital and traditional dentistry. This study assessed the linear dimensional accuracy of vinyl polysiloxane-based scannable and transparent BRMs over obligatory clinical time intervals (1, 24, 72, and 168 h/s). A total of 3 scannable [Flexitime Bite, Occlufast CAD, Virtual CADBite] and 3 transparent [Maxill Bite, Charmflex Bite, Defend ClearBite] VPS-based BRMs were divided into 28 subgroups by time interval: 1, 24, 72, and 168 h/s.

Assessing Cancer Knowledge in the General Population of Bisha Province, Saudi Arabia: A Cross-Sectional Study.

Background Cancer is a major cause of morbidity and mortality worldwide. It is anticipated that the number of new cases in Saudi Arabia will increase yearly as a result of significant changes in lifestyle and population development. There is little to no information or studies concerning cancer awareness or knowledge among the residents of Bisha Province.

Awareness of Obesity and Weight Loss Management Among Adults in the Asir Region, Saudi Arabia.

Obesity, a chronic disease marked by excessive fat accumulation and a body mass index (BMI) of 30 kg/m² or more, has become a major global health issue, affecting many adults worldwide and particularly prevalent in developed nations and Saudi Arabia. The condition can be caused by genetic, metabolic, and lifestyle factors. Understanding its awareness is imperative in designing effective health interventions.

Sepsis in Aging Populations: A Review of Risk Factors, Diagnosis, and Management.

Sepsis remains a significant global health concern, particularly among aging populations. This comprehensive review examines the complex interplay between aging and sepsis, focusing on risk factors, diagnostic challenges, and management strategies specific to older adults. The study explores the physiological changes associated with aging that contribute to increased sepsis susceptibility, including immunosenescence and chronic inflammation.

identification of potential peptide inhibitors to disrupt NLRP3 inflammasome complex formation by blocking NLRP3-ASC pyrin-pyrin interactions.

The NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) inflammasome is a well-known and frequently cited regulator of caspase-1 activation. It plays a significant role in several pathophysiological processes and is a major regulator of the innate immune response. A growing amount of scientific evidences for its aberrant activation in various chronic inflammatory diseases attracts a growing interest in the development of new NLRP3 inhibitors.