Characteristics of late recurrent candidemia in adult patients.

Background And Objectives: Candida species are one of the most common causes of health care-associated bloodstream infections. However, recurrent candidemia is rare, and the characteristics of late recurrent (LR) candidemia are partly unclear. Our aim was to evaluate the characteristics of LR candidemia in adult patients.

Persistent vs non-persistent candidaemia in adult patients in 2007-2016: A retrospective cohort study.

Objectives: Persistent candidaemia (PC) is a recognised complication of candidaemia. Our objective was to evaluate risk factors and clinical significance of PC in adult patients.

Methods: This is a retrospective, cohort study.

Clinical and microbiological factors associated with mortality in candidemia in adult patients 2007-2016.

Candidemia is a life-threatening infection with high mortality. Our aim was to evaluate the species distribution, antifungal susceptibilities and risk factors associated with 30-day mortality in candidemia in Southern Finland. We present a retrospective analysis of candidemia cases from the hospital district of Helsinki and Uusimaa during 2007-2016.

Clinical use of fungal PCR from deep tissue samples in the diagnosis of invasive fungal diseases: a retrospective observational study.

Objectives: To assess the clinical use of panfungal PCR for diagnosis of invasive fungal diseases (IFDs). We focused on the deep tissue samples.

Methods: We first described the design of panfungal PCR, which is in clinical use at Helsinki University Hospital.

The effect of vernal solar UV radiation on serum 25-hydroxyvitamin D concentration depends on the baseline level: observations from a high latitude in Finland.

Humans obtain vitamin D from conversion of 7-dehydrocholesterol in the skin by ultraviolet B (UVB) radiation or from dietary sources. As the radiation level is insufficient in winter, vitamin D deficiency is common at higher latitudes. We assessed whether vernal solar UVB radiation at latitudes 61°N and 67°N in Finland has an impact on serum 25-hydroxyvitamin D [S-25(OH)D] concentrations.