Dissociation between the expression of cGAS/STING and a senescence-associated signature in colon cancer.

Objective: The effect of the cGAS/STING pathway on antitumor immunity and its connection to senescence in vivo necessitates further investigation.

Introduction: Cellular senescence and its secretory phenotype (the SASP) are implicated in modulating the immune microenvironment of cancer possibly through the cGAS/STING pathway.

Methods: Gene expression data from paired colon cancer and adjacent non-malignant mucosa (98 patients,  = 196 samples; 65 patients,  = 130 samples) were analyzed for cGAS/STING and a senescence signature.

Iris-Claw Intraocular Lens Implantation in Pediatric Population: Indications, Outcomes, and a Comparison with Adult Population.

: The utilization of iris-claw intraocular lens (IOL) in adult cases of capsular insufficiency has been investigated. However, the use of iris-claw IOL in the pediatric population is still under investigation. In this study, we evaluated the overall practice of iris-claw IOL implantation in pediatrics and compared the visual outcomes and postoperative complication rates between children and adults.

Exploring the psychological effects of war on indirectly affected groups: a cross-sectional study on residents of Jordan.

The Gaza War has significantly escalated conflict and humanitarian crises in the Gaza Strip, causing profound human suffering and psychological impact. This study investigates the mental health of residents of Jordan, examining anxiety and depression levels, sociodemographic factors, and resilience mechanisms to understand the psychological resilience of communities facing conflict-related stressors. This cross-sectional study used a convenience sampling method to collect data from Jordanian residents over 18 years of age.

Awareness and Attitude Toward Artificial Intelligence Among Medical Students and Pathology Trainees: Survey Study.

Background: Artificial intelligence (AI) is set to shape the future of medical practice. The perspective and understanding of medical students are critical for guiding the development of educational curricula and training.

Objective: This study aims to assess and compare medical AI-related attitudes among medical students in general medicine and in one of the visually oriented fields (pathology), along with illuminating their anticipated role of AI in the rapidly evolving landscape of AI-enhanced health care.

Effect of poor glycemic control on the prevalence and determinants of anemia and chronic kidney disease among type 2 diabetes mellitus patients in Jordan: An observational cross-sectional study.

Background And Objectives: Anemia and chronic kidney disease (CKD) are common findings in diabetic patients. Lack of glycemic control is associated with increased risk of diabetic complications. This study aimed to determine the effect of poor glycemic control on the prevalence and determinants of anemia and CKD among type 2 diabetes mellitus (T2DM) patients in Jordan.