Publications by authors named "M Al Muderis"

: Giant cell tumor of bone (GCTB) is a locally aggressive tumor. It accounts for only 5% of all bony tumors. Early diagnosis, and follow-up for recurrence is often difficult due to a lack of biogenetic markers.

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  • Lower-extremity amputations are commonly caused by complications from diabetes mellitus and peripheral vascular disease, with traditional socket prostheses being the standard, while transcutaneous osseointegration for amputees (TOFA) is emerging as a potential alternative, particularly needing research for diabetic patients.* -
  • A study reviewed 17 patients with well-controlled diabetes who underwent unilateral transfemoral TOFA, tracking perioperative complications, additional surgeries, mobility, and quality of life over two years, finding no major systemic complications or deaths.* -
  • Results indicated that some patients experienced minor complications, but the majority showed significant improvements, such as an increase in daily prosthesis wear time from 36% to 79% of patients wearing it
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Background: Some amputees with transfemoral osseointegration (TFOI) have ipsilateral hip arthritis which can be addressed with total hip arthroplasty (THA). This study reported the medium-term outcomes of THA in association with TFOI (THA + TFOI).

Methods: Retrospective review was performed for eight patients with THA + TFOI performed at least 2 years prior.

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  • Upper limb (UL) amputation is a significant disability affecting daily life, with many patients dissatisfied with existing prosthetic options due to issues like lack of sensation and comfort.
  • Transcutaneous osseointegration (PFOI) offers a promising solution by surgically implanting a device that allows direct bone anchoring, improving prosthetic control and wear time without the bulk of a traditional socket.
  • The article outlines a surgical method for PFOI after forearm amputation, emphasizing careful technique to protect nerves and vessels, and highlights the importance of a motivated patient and engaged prosthetist for successful rehabilitation.
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Osseointegration implant (OI) surgery is the latest rehabilitation technology for amputees, where a bone-anchored implant obviates the limitations of traditional socket prostheses. The bone mineral density (BMD) in the periprosthetic and other anatomical regions can be used to assess bone remodelling following OI surgery. Currently, limited studies have used BMD measurements in reporting post-operative OI outcomes and the association between the maintenance of BMD and implant efficacy has remained elusive.

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