Publications by authors named "M Adamczak"

Both chronic kidney disease (CKD) and type 2 diabetes (T2D) are modern epidemics worldwide and have become a severe public health problem. Chronic kidney disease progression in T2D patients is linked to the need for dialysis or kidney transplantation and represents the risk factor predisposing to serious cardiovascular complications. In recent years, important progress has occurred in nephroprotective pharmacotherapy in CKD patients with T2D.

View Article and Find Full Text PDF

Fibroblast growth factor 21 (FGF21) is a protein hormone involved in physiological conditions in the regulation of energy expenditure and several metabolic processes. The aim of this present study was to analyze the effect of successful kidney transplantations on the plasma FGF21 concentration and to study the factors which may influence plasma FGF21 concentration in patients in long time after kidney transplantation. This study consisted of two independent parts.

View Article and Find Full Text PDF
Article Synopsis
  • Intravascular contrast media (ICM) are essential for medical imaging and treatment, but their use is often limited in patients with kidney issues due to fears of nephrotoxicity.
  • Historically, ICM was linked to kidney damage, leading to strict guidelines that restricted their use in patients with acute kidney injury (AKI) and chronic kidney disease.
  • Recent research has challenged these old views, revealing no direct causal link between ICM and kidney damage, prompting experts to propose updated guidelines that relax previous restrictions on ICM use in patients with impaired renal function.
View Article and Find Full Text PDF

In patients suffering from chronic kidney disease (CKD), substantial unfavourable alterations in the intestinal microbiota composition, i.e., dysbiosis, have been noted.

View Article and Find Full Text PDF

Sodium is the main cation in the extracellular space. In physiological conditions, sodium concentration in plasma is 135-145 mmol/l. The kidneys play the most important role in the regulation of sodium homeostasis.

View Article and Find Full Text PDF