Publications by authors named "M Aceves"
Article Synopsis
- The report investigates how adding a proton (cation) influences the electron transfer process in hydride transfer catalysis.
- A specific compound, protonated [HFeN(triethyl phosphine (PEt))(CO)], was created using benzoic acid and a reaction mixture, exhibiting a notable reduction potential.
- The study indicates that the electrochemical processes follow an ECEC mechanism, differing from previous models due to the presence of the proton, which makes the reduction of CO to formate or hydrogen more efficient.
Exploring Post-acute Care Challenges and Opportunities in Spinal Cord Injuries: Perspectives from 3 Distinct Countries: Canada, the United States, and Mexico.
Phys Med Rehabil Clin N Am
February 2025
This article describes the differences and similarities in post-acute care for patients with spinal cord injuries in Canada, the United States, and Mexico. It provides a comprehensive description of the current state of spinal cord injury post-acute care in each country, including the prevalent practices, rehabilitation continuum of care, as well as challenges and opportunities related to clinical services, psychosocial factors, economic considerations, and cultural influences.
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- Over 55 million people globally have dementia, with Alzheimer's Disease and Related Dementias (ADRD) constituting 60-70% of cases, leading to cognitive decline linked to neurodegeneration in key brain areas.
- Research indicates that increased endoplasmic reticulum (ER) stress may contribute to ADRD pathology by disrupting neurocellular homeostasis, particularly in regions involved in learning and memory.
- A study using induced pluripotent stem cell-derived neural stem cells found that ER stress, induced by thapsigargin, decreased NSC self-renewal and increased apoptosis, activating key UPR pathways that regulated gene expression and revealed significant changes in 2300 genes related to neurodegeneration.
A large portion of the heterogeneity in coronavirus disease 2019 (COVID-19) susceptibility and severity of illness (SOI) remains poorly understood. Recent evidence suggests that SARS-CoV-2 infection-associated damage to alveolar epithelial type 2 cells (AT2s) in the distal lung may directly contribute to disease severity and poor prognosis in COVID-19 patients. Our in vitro modeling of SARS-CoV-2 infection in induced pluripotent stem cell (iPSC)-derived AT2s from 10 different individuals showed interindividual variability in infection susceptibility and the postinfection cellular viral load.
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