Publications by authors named "M Abukhadra"

Familial Mediterranean Fever (FMF) is an inherited autosomal recessive disorder resulting from the inheritance of MEFV gene mutations. Patients with FMF are at increased risk of secondary amyloidosis, namely type AA. In some Mediterranean populations, the α genotype was associated with the development of renal amyloidosis, a finding not reproduced in other populations.

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  • - This research introduces a new type of photonic crystal called annular photonic crystals (APCs) designed for real-time detection of calcium carbonate scale in water pipelines.
  • - The sensor uses a circular layout of porous silicon with a central defect layer to monitor changes in refractive index, which indicates scale formation, and employs a modified transfer matrix method for analyzing reflectance.
  • - After extensive optimization of design parameters, the sensor achieved impressive performance metrics, including a QF of 1215 and high sensitivity, making it an efficient, cost-effective, and compact solution for monitoring scale buildup in water systems.
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Droplet microfluidic chips have emerged as an efficient platform for single-cell analysis due to their high sensitivity, efficiency, and throughput, showing significant potential in pathogen detection. However, current droplet microfluidic chips encounter challenges in large-scale droplet quantification and precise imaging, rendering them unsuitable for the high-throughput pathogen detection required for a large number of samples. To address these issues, this study developed a high-precision fluorescence imaging system utilizing a confocal reflective fluorescence approach, which is an advanced microscopy technique that combines confocal microscopy and reflected fluorescence imaging.

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  • - Natural glauconite was exfoliated to create methoxy exfoliated glauconite (Mth/EXG), which was tested for its ability to adsorb water contaminants like phosphate, safranin-O dye, and cadmium ions.
  • - Mth/EXG demonstrated impressive adsorption capacities: 269.9 mg/g for phosphate, 312 mg/g for safranin-O, and 234.5 mg/g for cadmium, outperforming more expensive adsorbents.
  • - The adsorption processes were governed by physical mechanisms such as hydrogen bonding and van der Waals forces, and the reactions were spontaneous and exothermic, indicating strong interactions with the pollutants even in complex chemical environments.
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In this study, eleven hydrazone-Schiff bases bearing benzimidazole moiety were synthesized successfully via three step reactions and structures of these products were deduced by HR-ESI-MS, H-, and C-NMR spectroscopic techniques. Lastly, these derivatives were tested for their in vitro urease inhibitory potential. Six compounds among the series attributed excellent inhibition with IC values of 7.

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