Drug repurposing of well-established drugs to be targeted against lung cancer has been a promising strategy. Bosentan is an endothelin 1 (ET-1) blocker widely used in pulmonary hypertension. The current experiment intends to inspect the anticancer and antiangiogenic mechanism of bosentan targeting epidermal growth factor receptor (EGFR) /extra-cellular Signal Regulated Kinase (ERK) /c-Jun/vascular endothelial growth factor (VEGF) carcinogenic pathway.
View Article and Find Full Text PDFIn this work, chitosan (Cs) was blended with different concentrations of Origanum majorana extract (OmE) for the formation of food packaging films. Based on the utilized volumes of OmE (2.5, 5, and 7.
View Article and Find Full Text PDFOrganophosphorus (OP) pesticides (e.g., parathion) and nerve agents (e.
View Article and Find Full Text PDFBackground: Research on marital happiness in Middle Eastern cultures is lacking. This lack of understanding has created several challenges for policymakers and marriage counselors as divorce rates have increased over the past decade.
Method: This study aimed to assess the prevalence of marital happiness among Omani couples and its association with demographic variables, including gender, level of education, and duration of marriage.
Objective: Aim: We aimed to assess selected measures of oral health, namely, enamel defect, eruption of permanent teeth, and dental caries. The nutritional status of orphans was investigated by physical examination, and then the nutritional status was correlated with measures of oral health.
Patients And Methods: Materials and Methods: A total of 192 orphans aged of 6 and 12 living in all orphanages in Baghdad, Iraq, were studied.