Exploring Mesenchymal Stem Cells versus Minoxidil for Androgenic Alopecia Treatment: A Detailed Animal-Based Histological and Morphometric Study.

Introduction: Androgenic alopecia (AGA), a hair loss condition caused by dihydrotestosterone binding to hair follicle receptors, negatively impacts quality of life for both men and women. Current treatments like minoxidil and finasteride have limitations, highlighting the need for alternative therapies, such as human umbilical cord blood-derived mesenchymal stem cells (HUCB-MSCs).

Methods: In this study, forty-eight adult male Wistar albino rats (3 months old) were used.

Optimizing in-situ upgrading of heavy crude oil via catalytic aquathermolysis using a novel graphene oxide-copper zinc ferrite nanocomposite as a catalyst.

Unconventional resources, such as heavy oil, are increasingly being explored and exploited due to the declining availability of conventional petroleum resources. Heavy crude oil poses challenges in production, transportation, and refining, due to its high viscosity, low API gravity, and elevated sulfur and metal content. Improving the quality of heavy oil can be achieved through the application of steam injection, which lowers the oil's viscosity and enhances its flow.

Combined eutexia and amorphization for simultaneous enhancement of dissolution rate of triamterene and hydrochlorothiazide: preparation of orodispersible tablets.

Background: Triamterene is an oral antihypertensive drug with dissolution-limited poor bioavailability. It can be used as monotherapy or in fixed dose combination with hydrochlorothiazide which also suffers from poor dissolution. Moreover, co-processing of drugs in fixed dose combination can alter their properties.

A potential role of mesenchymal stem cells derived from human umbilical cord blood in ameliorating psoriasis-like skin lesion in the rats.

Background: Psoriasis is a common autoimmune inflammatory skin disease, with no clear cause, treated with topical agents and phototherapy, conventional immunosuppressant drugs and biologic agents. Stem cell therapy has generated significant interest in regenerative medicine. The aim of this study was to use mesenchymal stem cell (MSC) therapy compared to the topical application of the standard conventional corticosteroid cream.