Publications by authors named "M Abiri"
Introduction: Preeclampsia (PE) is a serious pregnancy-related complication caused by high blood pressure in pregnant women. The severe form has more devastating effects. According to the growing evidence, the placenta is a crucial component in the pathogenesis of PE, and eliminating it will alleviate symptoms.
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- Hemoglobin Ernz (Hb Ernz) is a rare genetic variant in the β-globin gene, caused by a specific amino acid change and classified as uncertain by experts due to a lack of data.
- Over a span of more than 20 years of screening, eight cases of Hb Ernz were identified among individuals likely carrying thalassemia traits.
- The study suggests that the hematological issues observed in Hb Ernz individuals are more likely linked to mutations in the α-globin gene, advocating for a reclassification of Hb Ernz as a benign variant.
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- - Citrullinemia type 1 is a serious genetic disease that can cause dangerous levels of ammonia in the blood, potentially leading to coma or death in infants if not managed properly.
- - A study involving 7 families in Southwest Iran identified a common genetic mutation (exon 15 c.1168G A) linked to this condition, confirming that both parents were carriers.
- - The consistent presence of this mutation among affected families suggests a possible genetic cluster in that region, highlighting the need for genetic counseling and prenatal diagnosis.
45, X is a very rare condition that usually results from Y/autosomal translocations or insertions. Here we present an infertile azoospermic man who had 45, X t(Yp;15) karyotype and deletion of AZF (azoospermia factor) gene region. A 35-year-old infertile azoospermic man with a typical male appearance came for infertility genetic counseling.
View Article and Find Full Text PDFAlthough it has been about 30 years since the discovery of circular RNAs (circRNAs) in mammalian cells, these subtypes of RNAs' capabilities have come into focus in recent years. The unique structure and various functional roles of circRNAs in many cellular processes have aroused researchers' interest and raised many questions about whether circRNAs can facilitate the diagnosis and treatment of diseases. To answer these questions, we will illustrate the main known functions and regulatory roles of circRNAs in the cell after presenting a brief history of the discovery of circRNAs and the main proposed theories of the biogenesis of circRNAs.
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