Publications by authors named "M Abdul Roda"

Article Synopsis
  • The liver contains diverse populations of monocytes and macrophages, including liver-resident macrophages called Kupffer cells (KCs).
  • This text outlines a protocol for isolating KCs from human liver tissue removed during surgeries, detailing steps for tissue dissociation and cell separation.
  • It also includes instructions for validating the isolation process through immunofluorescence to confirm the presence of KCs by detecting the CD163 marker.
View Article and Find Full Text PDF

Objectives: To study the density, spacing, and regularity of retinal cone photoreceptors using an Adaptive Optics (AO) retinal camera (Rtx1, Imagine Eyes, Orsay, France) in patients with Primary Open Angle Glaucoma (POAG) and to compare the outcomes with those of healthy age-matched control subjects.

Methods: The study included 43 eyes with POAG and 31 eyes of normal subjects. POAG patients were divided into three groups according to the severity of the visual field defect.

View Article and Find Full Text PDF

Purpose: Osteoporotic fragility fractures (FF), particularly those affecting the hip, represent a major clinical and socio-economic concern. These fractures can lead to various adverse outcomes, which may be exacerbated by the presence of sarcopenia, especially among older and frail patients. Early identification of patients with FF is crucial for implementing effective diagnostic and therapeutic strategies to prevent subsequent fractures and their associated consequences.

View Article and Find Full Text PDF

Background & Aims: Transcription termination fine-tunes gene expression and contributes to the specification of RNA function in eukaryotic cells. Transcription termination of HBV is subject to the recognition of the canonical polyadenylation signal (cPAS) common to all viral transcripts. However, the regulation of this cPAS and its impact on viral gene expression and replication is currently unknown.

View Article and Find Full Text PDF