Publications by authors named "M Abdelbary"
The oral-gut axis is a complex system linking the oral cavity and gastrointestinal tract, impacting host health and microbial composition. This study investigates genetic changes and adaptive mechanisms employed by streptococci-one of the few genera capable of colonizing oral and intestinal niches-within the same individual. We conducted whole-genome sequencing (WGS) on 218 streptococcal isolates from saliva and fecal samples of 14 inflammatory bowel disease (IBD) patients and 12 healthy controls.
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- Hughes-Stovin syndrome (HSS) is a rare condition characterized by systemic vasculitis leading to both venous and arterial thrombosis, making it hard to differentiate from pulmonary embolism (PE) early on.
- This study compared 40 HSS patients to 50 PE patients, analyzing demographics, clinical findings, and results from computed tomography pulmonary angiography (CTPA).
- Results revealed that HSS patients were significantly younger and did not have co-morbidities like many PE patients; HSS showed unique vascular changes, including more frequent parenchymal hemorrhage and distinct pulmonary artery aneurysms.*
Background: Pulmonary arterial hypertension (PAH) is high blood pressure in the lungs that originates from structural changes in small resistance arteries. A defining feature of PAH is the inappropriate remodeling of pulmonary arteries (PA) leading to right ventricle failure and death. Although treatment of PAH has improved, the long-term prognosis for patients remains poor, and more effective targets are needed.
View Article and Find Full Text PDFEditorial: The oral-gut axis: from ectopic colonization to within-host evolution of oral bacteria.
Front Cell Infect Microbiol
February 2024