Publications by authors named "M Aasa"
Background: In uterine cervical cancer (UCC), tumour staging is performed according to the 2018 International Federation of Gynecology and Obstetrics (FIGO) system, where imaging is incorporated, or the more generic Tumour Node Metastasis (TNM) classification. With the technical development in diagnostic imaging, continuous prospective evaluation of the different imaging methods contributing to stage determination is warranted. The aims of this interim study were to (1) evaluate the performance of radiological FIGO (rFIGO) and T staging (rT) with 2-fluorine-18-fluoro-deoxy-glucose (2[18F]-FDG)-positron emission tomography with computed tomography (PET/CT) and with magnetic resonance imaging (PET/MRI), compared to clinical FIGO (cFIGO) and T (cT) staging based on clinical examination and conventional imaging, in treatment-naïve UCC, and to (2) identify possible MRI biomarkers for early treatment response after radiotherapy.
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- The study examined the impact of early ventricular arrhythmias (VAs) on the prognosis of patients with ST-segment elevation myocardial infarction (STEMI), focusing on the type and timing of these arrhythmias.
- Nonmonomorphic VT or VF was rare, occurring in only 3.4% of patients, but early VAs were linked to significantly higher risks of both in-hospital and longer-term mortality.
- Results indicated that VAs occurring after primary percutaneous coronary intervention (PCI) showed greater mortality risk compared to those before PCI, while the type of VA (monomorphic vs. nonmonomorphic) did not significantly influence long-term outcomes.
Background: The comparative efficacy of various anticoagulation strategies has not been clearly established in patients with acute myocardial infarction who are undergoing percutaneous coronary intervention (PCI) according to current practice, which includes the use of radial-artery access for PCI and administration of potent P2Y inhibitors without the planned use of glycoprotein IIb/IIIa inhibitors.
Methods: In this multicenter, randomized, registry-based, open-label clinical trial, we enrolled patients with either ST-segment elevation myocardial infarction (STEMI) or non-STEMI (NSTEMI) who were undergoing PCI and receiving treatment with a potent P2Y inhibitor (ticagrelor, prasugrel, or cangrelor) without the planned use of glycoprotein IIb/IIIa inhibitors. The patients were randomly assigned to receive bivalirudin or heparin during PCI, which was performed predominantly with the use of radial-artery access.
Article Synopsis
- - The study aimed to explore how chronic total occlusion (CTO) in coronary artery disease patients affects long-term mortality, utilizing data from a Swedish registry of over 90,000 patients who underwent coronary angiography between 2005 and 2012.
- - Findings indicated that patients with CTO had a significantly higher mortality rate (hazard ratio of 1.29) compared to those without CTO, particularly impacting younger patients (<60 years) and those with STEMI, while showing no difference based on sex or diabetes status.
- - The results highlight the serious prognostic implications of CTO, emphasizing the need for targeted treatment strategies in this patient population to potentially improve survival outcomes.
Aims: The aim of this study was to evaluate clinical outcome for different indications for PCI in an unselected, nationwide PCI population at short- and long-term follow-up.
Methods And Results: We evaluated clinical outcome up to six years after PCI in all patients undergoing a PCI procedure for different indications in Sweden between 2006 and 2010. A total of 70,479 patients were treated for stable coronary artery disease (CAD) (21.