Distribution and risk assessment of phenols and polycyclic aromatic hydrocarbons in sediments from the continental shelf adjacent to Nile River estuaries, Egypt.

Background: The highly industrialized areas characterize the delta coasts of the world, due to the discharging of large quantity of wastewater into the river estuaries. The entrance of phenolic compounds and PAHs into the aquatic environment has not been sufficiently studied on the Egyptian Mediterranean coast. The article examines the content and ecological risks associated with 11 phenolic compounds and 14 PAHs in the bottom sediments of the Nile River estuaries, the largest river systems that discharged into the Mediterranean Sea.

Functional anatomy and topographical organization of the frontotemporal arcuate fasciculus.

Traditionally, the frontotemporal arcuate fasciculus (AF) is viewed as a single entity in anatomo-clinical models. However, it is unclear if distinct cortical origin and termination patterns within this bundle correspond to specific language functions. We use track-weighted dynamic functional connectivity, a hybrid imaging technique, to study the AF structure and function in two distinct datasets of healthy subjects.

Heart Failure Beyond the Diagnosis: A Narrative Review of Patients' Perspectives on Daily Life and Challenges.

Heart failure (HF) is a complex syndrome that significantly affects patients' physical, psychological, and socioeconomic well-being. Despite advances in guideline-directed medical therapy (GDMT), such as ACE inhibitors, beta-blockers, and SGLT2 inhibitors, HF continues to have a high global burden, with over 64 million affected worldwide and a five-year mortality rate of 50%. HF disrupts various life aspects, especially for younger patients (aged 35-55), who often face career interruptions due to severe symptoms like fatigue and frequent hospitalizations.

A proliferation-inducing ligand (APRIL) level among risk factors of ocular involvement in patients with Behçet's disease.

Introduction: Ocular involvement is quite common in Behçet's disease (BD) and may cause crucial functional complications. Even though the mechanisms of BD remain unclear, advances in genetic and immunological fields have improved our understanding of the immunopathogenesis of BD ocular involvement. Little is known about the expression of a proliferation-inducing ligand (APRIL) in terms of ocular involvement in BD.

Efficacy and Safety of Prehospital Blood Transfusion in Traumatized Patients: A Systematic Review and Meta-Analysis.

Background: Approximately five million individuals have traumatic injuries annually. Implementing prehospital blood-component transfusion (PHBT), encompassing packed red blood cells (p-RBCs), plasma, or platelets, facilitates early hemostatic volume replacement following trauma. The lack of uniform PHBT guidelines persists, relying on diverse parameters and physician experience.