Radiolabeled Complex of Antimicrobial Peptides UBI29-41 and UBI18-35 Labeled with Tc for Differential Diagnosis of Bone Infection of the Limbs.

We studied an original radiolabeled complex of antimicrobial peptides UBI29-41 and UBI18-35, ubiquicidin derivatives, for distinguishing between bacterial and aseptic inflammation. For radiolabeling of the peptides with technetium-99m, a bifunctional chelating agent succinimide-1-yl 6-(bis(pyridin-2-ylmethyl)amino)hexanoate was used. The obtained complexes Тс-DPAH-UBI29-41 and Тс-DPAH-UBI18-35 had radiolabeling yield >80% and radiochemical purity >96%.

Experimental Simulation of Traumatic Osteomyelitis in Rats.

A model of traumatic osteomyelitis in rats is created. The disease development was evaluated by bone marrow myelograms, results of scintigraphy, and histological studies.

[Possibilities of a software-based hybrid single photon emission computed tomography/magnetic resonance imaging in the diagnosis of complicated diabetic foot syndrome].

Objective: To give the results of a software-based hybrid single photon emission computed tomography/magnetic resonance imaging (SPECT/MRI) in detecting osteomyelitis (OM) in patients with diabetic foot syndrome (DFS).

Material And Methods: Seventy-six patients (35 men and 41 women) (mean age, 59.4 +/- 7.

[Role of magnetic resonance imaging in the study of patients with diabetic foot syndrome].

Objective: To give the results of magnetic resonance imaging (MRI) in patients with complicated diabetic foot syndrome (DFS) to rule out or identify osteomyelitis.

Material And Methods: Twenty-seven (14 women and 13 men; mean age 60 ± 12.2 years) with type 1 and 2 diabetes mellitus and suspected osteomyelitis that had developed in the presence of DFS were examined.

[Different types of 199Tl chloride scintigraphic visualization of malignant tumors of the locomotor apparatus].

Background: 201Tl chloride scintigraphy allows malignant tumors of the locomotor apparatus to be diagnosed. The capacities of scintigraphy with 199Tl chloride, a 201Tl chloride analog, in addition to routine visualization of malignant tumors of the locomotor apparatus, have revealed its untypical variants.

Objective: to study the specific features of 199Tl chloride scintigraphic visualization of malignant tumor processes in the locomotor apparatus.