Publications by authors named "M A WOODBURY"
Background: There are no validated methods to identify individuals with cutaneous lupus erythematosus (CLE) from large databases including claims data and electronic health records, severely limiting the study of the epidemiology of this disease.
Objectives: To develop and validate accurate algorithms to identify individuals with CLE from healthcare records.
Methods: Twelve case-finding algorithms were developed based on the International Classification of Diseases (ICD)-10 diagnosis codes, provider specialty, and medication prescription data.
Astrocytes are crucial to brain homeostasis, yet their changes along the spatiotemporal progression of Alzheimer's disease (AD) neuropathology remain unexplored. Here we performed single-nucleus RNA sequencing of 628,943 astrocytes from five brain regions representing the stereotypical progression of AD pathology across 32 donors spanning the entire normal aging to severe AD continuum. We mapped out several unique astrocyte subclusters that exhibited varying responses to neuropathology across the AD-vulnerable neural network (spatial axis) or AD pathology stage (temporal axis).
View Article and Find Full Text PDFObjective: We sought to correlate the time lag between psoriatic arthritis (PsA) symptom onset and diagnosis to the likelihood and severity of depression, social impairment, and disease impact on quality of life.
Methods: This cross-sectional study conducted by the National Psoriasis Foundation (NPF) surveyed individuals with PsA using patient-reported outcome measures.
Results: The analysis cohort comprised 2,196 patients with PsA.
Article Synopsis
- Spatial neglect affects 20-80% of stroke survivors and can significantly lower their quality of life, with many experiencing long-term issues.
- Occupational therapists are well-suited to address this condition, but access to such therapy is limited, impacting patient care.
- A study found that only 4.9% of stroke survivors had a diagnostic code for spatial neglect, and among those diagnosed, just 2.3% received outpatient occupational therapy after leaving the hospital.
Article Synopsis
- This study looked at how being exposed to certain chemicals called phthalates during pregnancy could affect a baby's memory when they are around 7.5 months old.
- Phthalates are found in many products we use, and they might cause extra stress in the body, known as oxidative stress.
- The researchers found that higher levels of certain phthalates in pregnant mothers were linked to more oxidative stress and could affect how well babies remember new things.