From responsibility to responsibilization in stem cell research: An ethical framework.

Adopting a responsibilization approach can further improve the ethical conduct of stem cell (SC) research and applications. This approach helps align new and existing solutions for ethical implications by focusing on equipping SC researchers with the knowledge, skills, and organizational arrangements to take (co-)responsibility for the socio-ethical implications of their research.

The role of loading-induced convection versus diffusion on the transport of small molecules into the intervertebral disc.

Purpose: Limited nutrient transport is hypothesized to be involved in intervertebral disc (IVD) degeneration. It is widely recognized that the dominant mode of transport of small molecules such as glucose is via diffusion, rather than convection. However, recent findings suggest a role for convection-induced by fast (motion-related) and slow (diurnal) dynamic loading in molecular transport of even such small solutes.

Collagen Hydrolysates as Nutritional Support in Canine Osteoarthritis: A Narrative Review.

Osteoarthritis (OA) is a common disease in dogs with severe impact on their welfare. The multimodal management of OA includes feeding therapeutic diets and nutraceuticals to slow down OA progression. Collagen hydrolysates (CH) are a nutritional supplement that may exert anabolic effects on osteoarthritic joint cartilage as well as disease-modifying effects.

A novel spine tester TO GO.

Background: Often after large animal experiments in spinal research, the question arises-histology or biomechanics? While biomechanics are essential for informed decisions on the functionality of the therapy being studied, scientists often choose histological analysis alone. For biomechanical testing, for example, flexibility, specimens must be shipped to institutions with special testing equipment, as spine testers are complex and immobile. The specimens must usually be shipped frozen, and, thus, biological and histological investigations are not possible anymore.