Publications by authors named "M A Thirunarayan"

Article Synopsis
  • The study investigates the prevalence and impact of candidaemia in 67 ICUs across India, assessing how the COVID-19 pandemic influenced its rates and mortality.* -
  • Data from 401,601 patient days revealed higher candidaemia rates in COVID-19 ICUs (2.52/1000 patient days) compared to non-COVID-19 ICUs (1.05/1000 patient days), with associated mortality significantly higher in COVID-19 cases (61% vs. 41%).* -
  • Analysis identified C. tropicalis as the most common isolated species (26.7%), while C. auris, which had a high mortality rate, accounted for 17.5% of isolates
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This study included 21 newly isolated clinical samples of Streptococcus agalactiae (Group B Streptococcus) screened in patients (six male, fifteen female) from various states of India with different infections (urinary tract infections, blood, pus and eye infections). All isolates were identified as Group B Streptococcus (GBS) using hemolytic properties, serogrouping and MALDI-TOF-MS analysis. Six virulence genes, cfb (100%), cylE (90.

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Access to reverse transcription-PCR (RT-PCR) testing, the gold standard for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection, is limited throughout the world, due to restricted resources, available infrastructure, and high costs. Antigen-detecting rapid diagnostic tests (Ag-RDTs) overcome some of these barriers, but independent clinical validations in settings of intended use are scarce. To inform the World Health Organization's (WHO) emergency use listing (EUL) procedure and ensure affordable, high-quality Ag-RDTs, we assessed the performance and ease of use of the SureStatus for SARS-CoV-2.

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There is limited data on the gut colonization rate of colistin resistant (Col-R) bacteria in patients and healthy volunteers in India. Aim of this study was to investigate the stool carriage rate of Col-R in hospitalized patients. Stool samples were inoculated in Eosin Methylene Blue agar plates supplemented with colistin.

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Introduction: Antimicrobial-resistant HAI (Healthcare associated infection) are a global challenge due to their impact on patient outcome. Implementation of antimicrobial stewardship programmes (AMSP) is needed at institutional and national levels. Assessment of core capacities for AMSP is an important starting point to initiate nationwide AMSP.

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