Publications by authors named "M A Thaha"
Dysregulation of renin-angiotensin-aldosterone system (RAAS) often leads to hypertension and severe cardiorenal complications. Although RAAS-targeted therapies have proven effective, it remains yet optimal in reducing cardiovascular events. The aim of this study was to evaluate the efficacy and safety of angiotensin receptor neprilysin inhibitor (ARNI) compared to control in patients with hypertension.
View Article and Find Full Text PDFIntroduction: Hypertension is the leading noncommunicable disease case affecting 1.28 billion individuals worldwide, with most cases located in low- and middle-income countries. While there are numerous techniques for treating mild to moderate hypertension, properly controlling severe or resistant hypertension poses substantial challenges.
View Article and Find Full Text PDFBackground: Chronic kidney disease (CKD) is a significant global public health issue with increased risk of atherosclerotic cardiovascular disease (ASCVD) and cardiovascular mortality. Single nucleotide polymorphisms (SNPs) on angiotensin II type 1 receptor (AT1R) A1166C and osteoprotegerin (OPG) C950T gene have received significant attention as a genetic risk factor for cardiovascular disease and CKD.
Methods: This was a cross-sectional study involving 75 adults with CKD recruited from Nephrology Outpatient Clinics of Universitas Airlangga Hospital, Surabaya, Indonesia.
Article Synopsis
- The study investigates the long-term effects of chemoradiotherapy on the human rectum, focusing on inflammation, myenteric neuron changes, neuromuscular function, and the efficacy of prokinetic drugs.
- Researchers analyzed rectal tissue from patients who received chemoradiotherapy and compared it to tissues from those who did not, using various scientific methods to assess inflammatory status, neuronal structure, and muscle response.
- Results showed no significant inflammation or changes in myenteric neuron numbers, but chemoradiotherapy appeared to increase nitrergic-mediated muscle relaxations during nerve stimulation, indicating altered neuromuscular activity.
A review of modeling and control of remote-controlled capsule endoscopes.
Expert Rev Med Devices
April 2024
Introduction: The significance of this review lies in addressing the limitations of passive locomotion in capsule endoscopes, hindering their widespread use in medical applications. The research focuses on evaluating existing miniature in vivo remote-controlled capsule endoscopes, examining their locomotion designs, and working theories to pave the way for overcoming challenges and enhancing their applicability in diagnostic and treatment settings.
Areas Covered: This paper explores control methods and dynamic system modeling in the context of self-propelled remote-controlled capsule endoscopes with a two-mass arrangement.