Publications by authors named "M A Tecce"
Type 1 diabetes (T1D) severely impairs metabolic control and can lead to erectile dysfunction (ED) through hyperglycemia-induced vascular damage, autonomic neuropathy, and psychological distress. This review examines the role of continuous glucose monitoring (CGM) in ameliorating ED by addressing glucose variability and inflammation. A comprehensive analysis of studies and clinical trials was conducted to evaluate the impact of CGM on metabolic control, inflammatory responses, and vascular health in patients with T1D.
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- * The new compounds were rigorously tested using FRET analysis and showed strong inhibition of Haspin, with some identified as the most promising candidates in cellular models when combined with paclitaxel, enhancing its effectiveness.
- * Additional testing of these inhibitors revealed significant selectivity among 70 different kinases, and further chemical insights were gained, suggesting that these derivatives warrant more in-depth research for potential therapeutic use.
Heart failure (HF) management in type 1 diabetes (T1D) is particularly challenging due to its increased prevalence and the associated risks of hospitalization and mortality, driven by diabetic cardiomyopathy. Sodium-glucose cotransporter-2 inhibitors (SGLT2-is) offer a promising avenue for treating HF, specifically the preserved ejection fraction variant most common in T1D, but their utility is hampered by the risk of euglycemic diabetic ketoacidosis (DKA). This review investigates the potential of SGLT2-is in T1D HF management alongside emergent Continuous Ketone Monitoring (CKM) technology as a means to mitigate DKA risk through a comprehensive analysis of clinical trials, observational studies, and reviews.
View Article and Find Full Text PDFBackground: A comprehensive understanding of changes in health-related quality of life after head and neck cancer surgery is necessary for effective preoperative counseling. The goal of this study was to perform a longitudinal analysis of postoperative quality of life outcomes after fibula free flap (FFF) mandible reconstruction.
Methods: A retrospective review was performed for all patients who underwent oncologic mandible reconstruction with an FFF between 2000 and 2021.
Background: The use of deep inferior epigastric perforator (DIEP) flaps is a well-established breast reconstruction technique.
Methods: A 29-question survey was e-mailed to 3186 active American Society of Plastic Surgeons members, aiming to describe postoperative monitoring practice patterns among surgeons performing DIEP flaps.
Results: From 255 responses (8%), 79% performing DIEP surgery were analyzed.