Publications by authors named "M A TAMARKIN"
Objective: To develop novel fetal reference ranges for the characterization of the normal appearance of the Sylvian fissures (SF) along gestation and to apply them to fetuses with cortical abnormalities affecting the SF.
Methods: In this cross-sectional study, we used three-dimensional sonographic multiplanar reformatting (3D-MPR) to examine the fetal SF. Normal development was assessed in the second and third trimesters.
Prenatal diagnosis of rhombencephalosynapsis: neuroimaging features and severity of vermian anomaly.
Ultrasound Obstet Gynecol
December 2021
Objectives: To describe the prenatal neuroimaging spectrum of rhombencephalosynapsis (RES) and criteria for its classification according to the severity of vermian anomaly.
Methods: In this multicenter retrospective study of fetuses with RES between 2002 and 2020, the medical records and brain ultrasound and magnetic resonance images were evaluated comprehensively to determine the severity of the vermian anomaly and the presence of associated brain findings. RES was classified, according to the pattern of vermian agenesis and the extent of the fusion of the hemispheres, as complete RES (complete absence of the vermis) or partial RES (further classified according to the part of the vermis that was missing and, consequently, the region of hemispheric fusion, as anterior, posterior, severe or mixed RES).
Objective: The purpose of this study was to establish prognostic factors in fetuses diagnosed with periventricular pseudocysts (PVPCs) without known congenital infection, between 28 and 37 weeks of gestation.
Methods: This retrospective study included cases of fetal PVPC from 2008 to 2018. PVPCs were classified according to location, number, extension, morphology, and size.
Article Synopsis
- The study aims to identify a specific neuroimaging characteristic of prenatal PHACES syndrome (PS), specifically focusing on unilateral cerebellar hypoplasia (UCH) and its relationship with a cyst in the posterior fossa and the 4th ventricle.
- Researchers analyzed records from seven prenatal diagnosis centers, assessing ultrasound and MRI findings in cases diagnosed with PS after birth, and compared these findings to cases with UCH not associated with PS.
- Results showed that PS fetuses exhibited a distinctive "tilted telephone receiver sign" (TTRS) in their cerebellar structure, which was absent in non-PS cases, indicating that TTRS can aid in the prenatal diagnosis of PHACES syndrome.
Objectives: To elaborate the imaging phenotype associated with a homozygous c.743C > del frameshift mutation in DAG1 leading to complete absence of both α- and β-dystroglycan previously reported in a consanguineous Israeli-Arab family.
Methods: We analyzed prenatal and postnatal imaging data of patients from a consanguineous Israeli-Arab kindred harboring the DAG1 mutation.