Police Contact, Sleep, and Mental Health in the Adolescent Brain Cognitive Development (ABCD) Study.

Using data from the Adolescent Brain Cognitive Development study (n = 3928), we examined how police contact relates to sleep problems, anxiety, and depressive symptoms during middle adolescence (M age = 14.09; SD = 0.68).

Quantum Dot Erythropoietin Bioconjugates Enhance EPO-Receptor Clustering on Transfected Human Embryonic Kidney Cells.

Erythropoietin (EPO)-induced cellular signaling through the EPO receptor (EPOR) is a fundamental pathway for the modulation of cellular behavior and activity. In our previous work, we showed in primary human astrocytes that the multivalent display of EPO on the surface of semiconductor quantum dots (QDs) mediates augmented JAK/STAT signaling, a concomitant 1.8-fold increase in the expression of aquaporin-4 (AQPN-4) channel proteins, and a 2-fold increase in the AQPN-4-mediated water transport activity.

Optimizing Prescribing for Individuals With Type 2 Diabetes and Chronic Kidney Disease Through the Development and Validation of Algorithms for Community Pharmacists.

Background: Diabetes is the leading cause of kidney disease and contributes to 38% of kidney failure requiring dialysis. A gap in detection and management of type 2 diabetes (T2D) in chronic kidney disease (CKD) exists in primary care. Community pharmacists are positioned to support those not able to access kidney care through traditional pathways.

Systematic ocular phenotyping of 8,707 knockout mouse lines identifies genes associated with abnormal corneal phenotypes.

Purpose: Corneal dysmorphologies (CDs) are typically classified as either regressive degenerative corneal dystrophies (CDtrs) or defective growth and differentiation-driven corneal dysplasias (CDyps). Both eye disorders have multifactorial etiologies. While previous work has elucidated many aspects of CDs, such as presenting symptoms, epidemiology, and pathophysiology, the genetic mechanisms remain incompletely understood.

Pneumonia and Anemia in Rural Midwestern Missouri: A Retrospective Analysis.

Introduction: Pneumonia and anemia are prevalent medical conditions with significant implications on patient health, resulting in numerous hospitalizations and deaths. Various studies have been done on the mortality rates of pneumonia and anemia individually. However, fewer describe the mortality of patients diagnosed with pneumonia superimposed on anemia.