Publications by authors named "M A Spear"
Wood modification using low molecular weight thermosetting resins improves the biological durability and dimensional stability of wood while avoiding increasingly regulated biocides. During the modification process, resin monomers diffuse from the cell lumen to the cell wall, occupying micropore spaces before curing at 150 °C. This study investigated the mechanism of cell wall diffusion at multiple scales, comparing two test groups where diffusion was either facilitated or restricted.
View Article and Find Full Text PDFObjectives: To measure physical activity in a cohort of children who survived greater than or equal to 3 days of invasive ventilation.
Design: Prospective cohort study (2018-2021).
Setting: Quaternary children's hospital PICU.
Article Synopsis
- Freshwater ecosystems are important for studying how invasive species affect biological communities, particularly using insights from long-term research in North Temperate Lakes.
- Key findings indicate that invasive species are often more common than previously thought, tend to be in low numbers, and can rapidly increase in response to environmental changes.
- The study highlights the potential for significant impacts on ecosystems, the importance of monitoring reservoirs as hotspots for invasions, and that removal efforts can benefit ecosystems in the long run.
Persistence of human immunodeficiency virus (HIV) reservoirs prevents viral eradication, and consequently HIV-infected patients require lifetime treatment with antiretroviral therapy (ART) [1-5]. Currently, there are no effective therapeutics to prevent HIV rebound upon ART cessation. Here we describe an HIV/SIV Rev-dependent lentiviral particle that can be administered to inhibit viral rebound [6-9].
View Article and Find Full Text PDFRivers are increasingly used as superhighways for the continental-scale transportation of freight goods, but the ecological impact of large vessel traffic on river ecosystems is difficult to study. Recently, the temporary maintenance closure of lock and dam systems on the Illinois Waterway (USA) brought commercial vessel traffic to a halt along the river's length, offering a rare opportunity to study the response of the ecosystem before, during, and after an extended pause of this persistent anthropogenic disturbance. We observed improvements in main- and side-channel water quality and a redistribution of fish habitat-use during a months-long, near-complete reduction of large vessel traffic.
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