Differential effects of liraglutide naltrexone/bupropion, and caloric restriction on metabolic parameters and beta-cell regeneration in type 2 diabetic rat model: role of beta arrestin 1.

Traditional antidiabetic treatments often carry the risk of beta-cell exhaustion, highlighting the need for therapies that promote beta-cell regeneration. This study investigates the comparative effects of Liraglutide, naltrexone/bupropion (NTX + BUP), and caloric restriction on metabolic control and beta-cell regeneration in a rat model of obese type 2 diabetes. Fifty male albino rats were randomized into five groups: normal control, diabetic control, diabetic + caloric restriction (50%), diabetic + NTX + BUP (4 mg/45 mg /kg/day orally), and diabetic + liraglutide (0.

Investigating the Medicinal Potential of Leaf Extract: Phytochemical Profiling and In Vitro Evaluation of Antimicrobial, Antioxidant, and Anticancer Activities.

This study investigated the medicinal potential of , a plant traditionally known for its therapeutic properties. The aim was to identify the phytocompounds in leaf extract and evaluate its antibacterial, antioxidant, and anticancer effects. Gas chromatography-mass spectrometry analysis was employed to characterize the phytochemical composition of the ethanol extract derived from leaves.

Exploring the lead-free halide CsMGaBr (M = Li, Na) double perovskites for sustainable energy applications.

In recent years, there has been a growing emphasis on the exploration of sustainable and eco-friendly materials well-suited for advanced applications in the realms of thermoelectrics and optoelectronics. Lead-free halide double perovskites have emerged as a compelling class of materials in this context. Nevertheless, despite their potential utility, thorough investigations into their thermal transport characteristics remain limited.

Oral glutamine: Is there a role in the amelioration of radiation-induced mucositis? A prospective case-control study at a tertiary care centre in North India.

Background: The most frequently occurring painful and dose-limiting side effect of radiation therapy (RT) to the head and neck region is oral mucositis (OM). Several studies demonstrated that glutamine may reduce the severity and the duration of OM significantly during RT and chemo-radiotherapy in patients with head and neck cancer (HNC).

Materials And Methods: Between January 2021 and August 2022, a prospective single institutional case-control study compared the efficacy and safety of oral glutamine on radiation-induced mucositis in patients with HNC.

A Review on Cementitious and Geopolymer Composites with Lithium Slag Incorporation.

This study critically reviews lithium slag (LS) as a supplementary cementitious material (SCM), thereby examining its physiochemical characteristics, mechanical properties, and durability within cementitious and geopolymer composites. The review reveals that LS's particle size distribution is comparable to fly ash (FA) and ground granulated blast furnace slag (GGBS), which suggests it can enhance densification and nucleation in concrete. The mechanical treatment of LS promotes early hydration by increasing the solubility of aluminum, lithium, and silicon.