Antibacterial and anti-inflammatory activities of marine .

The marine environment covers three quarters of the surface of the planet and is estimated to be home to more than 80% of life but yet it remains largely unexplored. It harbours a number of macro and microorganisms that have developed unique metabolic abilities to ensure their survival in diverse and hostile habitats, resulting in the biosynthesis of an array of secondary metabolites with specific activities. In this study, pigment forming bacterial strains were isolated from the sea surface inter tidal zones at different sampling sites along the Visakhapatnam coastal region.

In -silico molecular docking analysis of prodigiosin and cycloprodigiosin as COX-2 inhibitors.

Prodigiosin and cycloprodigiosin are tripyrrole red pigmented compounds with medical importance for their anticancer property. In the present investigation, molecular docking studies were performed for both prodigiosin and cycloprodigiosins to evaluate the in- silico anti-inflammatory activity against Cycloxigenase-2 (COX-2) protein as model compound and the data compared with rofecoxib and celcoxid. Cycloprodigiosin showed higher initial potential, initial RMS gradient and potential energy values compared to prodigiosin.

Antibacterial activity of some folklore medicinal plants from South India.

Antibacterial activity and phytochemical tests of eight whole plant methanol extracts belonging to family Euphorbiaceae were evaluated. In agar well diffusion assay the diameter of inhibition zones ranged from 3-13 mm. Phyllanthus emblica showed maximum activity of 13 mm.

Decolourisation of textile and dye amended soils by fungi.

Four fungi viz. Aspergillus niger, Curvularia lunata, Fusarium oxysporum, Mucor mucedo isolated from textile and dye contaminated soils were tried for their efficiency in colour removal. The physical, chemical and biological characteristics were analysed and related to the process of decolourisation.