Publications by authors named "M A Shehab"

Platelets are hyperactive in patients with type2 diabetes (T2DM), they adhere to vascular endothelium and play a key role in macrovascular complications. Platelets activity can be measured by flow-cytometry (cluster of differentiation (CD) 41, CD 42, CD 62, CD 63), which allows detection of surface antigens in a sensitive and specific manner. This study aimed to describe platelets activity in T2DM in association with cardiovascular and cerebrovascular complications in relation to duration of diabetes (DM).

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Introduction: Biologic therapies treat patients with moderate to severe inflammatory bowel disease (IBD). This study aims to investigate the demographics of biologic therapy use and its association with patient characteristics, a topic that has not yet been thoroughly assessed in our region.

Methods: Electronic health record data from June 1, 2021, to May 31, 2023, were collected at a tertiary care IBD center in Kuwait.

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Biomass is a key element in biofuels which can be defined as a fuel produced through contemporary biological processes, and its increased use can support the EU's aims of reducing greenhouse gas emissions. Information on the nature and the quality of the biomass or biofuel is important in order to support the optimization of their combustion with respect to realizing higher efficiencies and lower emissions during energy production. Three reference materials were produced by a collaborative approach among national metrology institutes and designated institutes within the scope of the EMPIR project: BIOFMET.

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Article Synopsis
  • The study investigates Dipeptidyl peptidase-4 (DPP4) enzyme activities in young individuals diagnosed with type 2 diabetes mellitus (T2DM) compared to those with normal glucose tolerance (NGT).
  • It involved 29 young participants with untreated T2DM and 29 participants with NGT, measuring various health metrics and DPP4 enzyme activity levels.
  • Results showed that T2DM participants had significantly higher DPP4 activity than those with NGT, suggesting a potential link between elevated DPP4 levels and youth-onset T2DM.
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Article Synopsis
  • A study was conducted to evaluate the effectiveness of biologic therapies in treating inflammatory bowel disease (IBD) patients in the Middle East, focusing on biologic-naïve individuals.
  • The research analyzed records of 422 patients treated with different biologics (adalimumab, infliximab, ustekinumab, vedolizumab) over a period from October 2017 to October 2023, measuring outcomes like hospitalizations, surgeries, and remission rates.
  • Results showed that biologics were effective in achieving remission for both Crohn's disease and ulcerative colitis, indicating that their efficacy in this region is comparable to that seen in Western populations.*
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