H2O outgassing from silica-filled polysiloxane TR55.

Temperature-programmed desorption/decomposition (TPD) was employed to obtain the moisture content and outgassing kinetics of TR55, a silica-filled cross-linked polysiloxane. The total moisture content of TR55 in the as-received state and after 20-30 min of vacuum pumping in the load-lock prior to TPD was measured to be on the order of 0.35 wt%.

Gas chromatographic method for the simultaneous determination of S-p-toluylmercapturic acid and S-phenylmercapturic acid in human urine.

An analytical method for the simultaneous determination of S-p-toluylmercapturic acid (p-TMA) and S-phenylmercapturic acid (PMA) in human urine is described. PMA is a common biomarker for benzene exposure, whereas p-TMA is detected for the first time in the urine of workers occupationally exposed to toluene. Before analysis, the acidified urine samples were spiked with S-(p-fluorine)-phenylmercapturic acid as internal standard.

S-p-toluylmercapturic acid in the urine of workers exposed to toluene: a new biomarker for toluene exposure.

A mercapturic acid attached to the aromatic ring of toluene was for the first time detected in human urine as a metabolite of toluene. Since the metabolism of toluene is usually considered to take place at the side-chain, this gives, besides the biosynthesis of cresols, a further hint of a metabolic conversion of the aromatic system. We examined a group of 33 workers occupationally exposed to toluene, determining the concentrations of toluene in ambient air and in whole blood, o-cresol and hippuric acid in urine and p-toluylmercapturic acid (p-TMA) in urine.