Publications by authors named "M A Sahraian"
Background: Cognitive impairment (CI) is one of the main features of multiple sclerosis (MS). Cognitive rehabilitation (CR) programs are crucial for improving cognition and computer-assisted cognitive rehabilitation is considered as an effective method for cognition rehabilitation. To assess the effects of computer-based cognitive rehabilitation program on cognition in patients with multiple sclerosis (MS).
View Article and Find Full Text PDFThe impact of social and environmental factors on triggering multiple sclerosis onset, before and during the COVID-19 pandemic: a retrospective study from Iran.
BMC Neurol
November 2024
Background: Multiple sclerosis (MS) is a chronic, inflammatory, and demyelinating disease of the central nervous system. The first presentation's possible triggers are still controversial among scientists. The objective of this study is to investigate and compare the potential social, environmental, and physical factors that may have contributed to the onset of MS before and during the Coronavirus Disease 2019 (COVID-19) pandemic.
View Article and Find Full Text PDFArticle Synopsis
- - Multiple sclerosis is a serious condition, and the study compared the efficacy and safety of a biosimilar drug called Xacrel to the original drug, Ocrevus, in patients with Relapsing Multiple Sclerosis (RMS) over 96 weeks.
- - The main goal was to see if both drugs had similar effects on reducing annual relapse rates (ARR) at 48 weeks, while also assessing other factors like disability progression, MRI results, and safety.
- - Results showed that Xacrel was equivalent to Ocrevus in reducing ARR, with no significant differences in efficacy or safety observed during the trial, confirming Xacrel as a viable alternative to Ocrevus.
Providing informal care can deeply influence, both physically and emotionally, the quality of life (QoL) of caregivers, especially when the disease becomes chronic. CarerQol-7D is one of the most common instruments for measuring informal care. We aimed to develop a Persian version of the CarerQol-7D in the context of Iranian caregivers of patients with multiple sclerosis (MS).
View Article and Find Full Text PDFInvestigating the Correlation Between Cognitive Function and Fasting Blood Sugar, Fasting Insulin Level and Insulin Sensitivity in Patients With Multiple Sclerosis.
Endocrinol Diabetes Metab
November 2024
Article Synopsis
- A study was conducted to explore how fasting blood sugar (FBS), fasting insulin, and insulin sensitivity relate to cognitive impairment (CI) in multiple sclerosis (MS) patients.
- The research involved 85 MS patients, measuring their cognitive abilities and insulin sensitivity, showing various correlations between these factors and cognitive test scores.
- Findings suggest that higher FBS and insulin levels, along with lower insulin sensitivity, may predict cognitive impairment in MS patients.