Publications by authors named "M A Repo"
Article Synopsis
- Gastrointestinal endoscopy is widely used in children with abdominal issues, and while atrophic duodenal changes are often linked to celiac disease, the implications of non-atrophic duodenal changes are less understood.
- In a study of 1,170 children, 4.4% had non-atrophic changes; common findings included non-specific inflammation and intraepithelial lymphocytosis, with affected patients showing higher instances of blood in stools, anemia, and positive celiac serology compared to those with normal findings.
- During long-term follow-up, some patients with initial non-atrophic changes developed celiac disease, indicating the need for ongoing monitoring even when formal diagnoses are not established at
Article Synopsis
- Low ferritin levels are commonly observed in patients with screen-detected coeliac disease, with 21% showing ferritin levels under 15 μg/L and 40% under 30 μg/L at diagnosis, despite being non-anaemic.
- After 1-2 years on a gluten-free diet (GFD), ferritin levels improved significantly from a median of 41.5 μg/L to 86.0 μg/L, yet 21% of patients still had ferritin levels under 30 μg/L.
- Interestingly, low ferritin levels didn't correlate with the severity of symptoms, quality of life, or other health indicators, suggesting that even though low ferritin is common in these patients
Article Synopsis
- * Out of 239 adult patients, 180 followed a strict gluten-free diet, but 18% reported ongoing symptoms, primarily gastrointestinal issues, along with fatigue and joint pain.
- * Patients with persistent symptoms had greater health concerns and a lower quality of life compared to those without symptoms, and none of the childhood diagnosis features predicted symptom persistence in adulthood.
Purpose: We evaluated adherence to a gluten-free diet and associated factors in adult celiac disease patients diagnosed in childhood.
Methods: Comprehensive medical data on 955 pediatric celiac disease patients was collected and study questionnaires sent to 559 who were now adults. All variables were compared between strictly adherent and non-adherent patients.
Objective: Assessment of the upper gastrointestinal tract (UGI) may enable more personalized treatment strategies in pediatric inflammatory bowel disease (IBD). However, data on the frequency and significance of these findings remain limited.
Methods: Data on 132 pediatric IBD patients with systematic UGI sampling were collected and the baseline characteristics and presence of complications compared between those with and without histological UGI findings.