Outcomes of Aortobiiliac versus Aortobifemoral Bypass in Patients with Aortoiliac Occlusive Disease: A National Multi-Institutional Study.

Introduction: This study aims to evaluate perioperative and one-year outcomes of patients undergoing aortobiiliac bypass (ABIB) in comparison with aortobifemoral bypass (ABFB) for the treatment of aortoiliac occlusive disease, using data from the Vascular Quality Initiative (VQI).

Methods: All patients undergoing ABIB and ABFB bypasses (2010-2023) were queried. The primary outcome was surgical site infections (SSI).

Cerebral Hyperperfusion Syndrome After Carotid Revascularization; Predictors and Complications.

Objectives: Cerebral hyperperfusion syndrome (CHS) is a rare but serious complication following carotid artery revascularization. Considering the varying rates observed among carotid endarterectomy (CEA), Transfemoral Carotid Artery Stenting (TFCAS), and Transcarotid Artery Revascularization (TCAR), identifying the predictors and complications of CHS is essential for improving patient outcomes. This study utilizes a national database to investigate the predictors and complications of CHS following carotid revascularizations.

Long-Term Follow Up in Anti-Contactin-1 Autoimmune Nodopathy.

Objective: To analyze long-term clinical and biomarker features of anti-contactin-1 (CNTN1) autoimmune nodopathy (AN).

Methods: Patients with anti-CNTN1 autoimmune nodopathy detected in our laboratory from which clinical information was available were included. Clinical features and treatment response were retrospectively collected.

Endothelial Cell Senescence Effect on the Blood-Brain Barrier in Stroke and Cognitive Impairment.

Age is an important risk factor of stroke, cognitive decline, and dementia. Senescent endothelial cells (ECs) accumulate with advancing age through exposure to cellular stress, such as that exerted by hypertension and diabetes. These senescent ECs have altered characteristics, such as altered tight junction proteins, use of a more indiscriminate transcellular transport system, increased inflammation, and increased immune cell interactions.