Identification and structural analysis of pathogenic variants in MYOC and CYP1B1 genes in Indian JOAG patients.

Purpose: Juvenile onset open-angle glaucoma (JOAG) manifests in individuals under the age of 40, resulting in elevated intraocular pressure and significant optic nerve damage. To broaden the spectrum of mutations associated with JOAG and to determine their specific structural implications, we examined Myocilin and Cytochrome P450 1B1 gene in a cohort of 111 unrelated North Indian patients diagnosed with JOAG.

Study Design: A clinical and experimental study.

A Neurological Disease, (Ptosis), Managed with Integrated Management of Modern Science and - A Case Report.

Introduction: Ptosis is when the upper eyelid droops downward. However, a droopy eyelid can cover the pupil and reduce vision in some cases. Causative factors may be congenital, injury or stretching of eyelid muscles or ligaments damage to the nerve controlling the eyelid muscles, aging, a complication of eye surgery, a complication of Botox injections.

Viral Infection Associated Membranous Nephropathy: Clinical Presentation and Outcomes.

Background: Viral infections can increase the likelihood of an individual developing membranous nephropathy (MN). Limited information is available regarding the treatment approaches for such cases. We conducted a review focusing on hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency virus (HIV)-associated MN.

Microsurgical Semilunar Bilaminar Technique Halts Progression of Marginal Tissue Recession by Soft Tissue Phenotypic Modification-A Case Report With 3-Year Follow-Up.

Phenotype modification therapy using the novel semilunar flap with xenogeneic collagen matrix improves gingival phenotype, root coverage and increased keratinized tissue width. It also halts the progression of recession, enhances tissue resilience and improved plaque control sustainable over 3 years. Collagen matrix avoids second site surgery and hence less morbidity.

Comprehensive Review on Tinea Infection Therapies: Allopathic and Herbal Approaches for Dermatophytosis.

Background: Tinea infections are superficial fungal infections caused by three species of fungi (i.e. Epidermophyton, Microsporum, and Trichophyton) collectively termed dermatophytes.