Publications by authors named "M A Rane"
The test-negative design (TND) is widely used to estimate COVID-19 vaccine effectiveness (VE). Biased estimates of VE may result from effects of at-home SARS-CoV-2 rapid diagnostic test (RDT) results on decisions to seek healthcare. To investigate magnitude of potential bias, we constructed decision trees with input probabilities obtained from longitudinal surveys of U.
View Article and Find Full Text PDFWith agricultural demands increasing globally, determining the nature of impacts of different forms of agriculture on biodiversity, especially for threatened vertebrates and habitats, is critical to inform land management. This is especially true for open ecosystems such as the natural rock outcrops and amphibians, both of which are threatened by land-use change. Lateritic plateaus of the northern Western Ghats are rock outcrop ecosystems harboring endemic biodiversity.
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- Left atrial appendage closure (LAAC) is used as an alternative stroke prevention method for patients who cannot take blood thinners, but pulmonary artery injury (PAI) is a rare and serious complication associated with it.
- A review of previous PAI cases and data from the FDA's MAUDE database identified 36 cases, predominantly involving older patients, and highlighted that PAI often presents soon after the procedure, with a significant percentage requiring surgery.
- The study emphasizes the need for heightened awareness of PAI symptoms post-LAAC, especially concerning rapid fluid accumulation around the heart, even without clear predictive signs from imaging or clinical details.
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- The study examines cachexia in cancer patients, which is a syndrome causing muscle and cardiac deterioration, and explores how withaferin A (WFA) treatment can help mitigate these effects.
- Researchers created a model by injecting NSG mice with ovarian cancer cells and treated them with WFA to assess its impact on kidney damage in addition to muscle and cardiac function.
- Results indicate that tumor-bearing mice exhibited elevated inflammatory markers and kidney damage, but WFA treatment significantly reduced these harmful effects compared to control groups.
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- Neutrophil degranulation contributes to kidney damage in proliferative lupus nephritis (LN), suggesting it plays a role in the illness's progression.
- Measuring specific neutrophil granule proteins in urine could help diagnose and monitor the severity of proliferative LN in patients.
- The study found that urine levels of eight neutrophil granule proteins were significantly higher in patients with active LN compared to healthy individuals, and decreases in these proteins correlated with clinical remission.