Publications by authors named "M A Randolph"
Article Synopsis
- Uterus transplantation is currently the only solution for women with absolute uterine infertility, such as those with Rokitansky syndrome, allowing them to experience pregnancy and childbirth.
- There are significant challenges with uterus transplantation, including the risks of ischemia-reperfusion injury and a notable thrombotic complication rate of up to 20%, which can lead to graft rejection.
- This protocol aims to outline the surgical steps for obtaining porcine uteruses and implementing dynamic preservation through machine perfusion, which may reduce hypoxic injury compared to traditional static cold storage methods.
Osteosarcoma (OS) is the most common primary malignant bone tumor in childhood. Patients who present with metastatic disease at diagnosis or relapse have a very poor prognosis, and this has not changed over the past four decades. The Wnt signaling pathway plays a role in regulating osteogenesis and is implicated in OS pathogenesis.
View Article and Find Full Text PDFSjogren's disease, well-described in people, is rarely identified in veterinary species. In people, Sjogren's disease is one of the most common systemic autoimmune disorders with an incidence of 0.5% in the female population.
View Article and Find Full Text PDFArticle Synopsis
- The study tests the hypothesis that delivering soluble allogeneic type I telocollagen would enhance tendon healing, based on its properties that help in integrating into damaged connective tissue with minimal immune response.
- Ninety-eight shoulders from Sprague-Dawley rats were surgically manipulated, with different treatments (saline, allo-telocollagen, or allo-atelocollagen) applied after tendon repair, and outcomes assessed at 30 and 60 days post-surgery through mechanical tests and histological analysis.
- Results showed that by 60 days, allo-telocollagen significantly improved the mechanical properties of the supraspinatus tendon compared to saline and allo-atelocollagen, showing better strength and
Objective: To examine chiropractic students' attitudes regarding knowledge of pain neuroscience, chronic pain, and patient-centered care before and after educational interventions. Secondarily, this study aimed to compare measures of these skills between cohorts at different timepoints throughout training programs.
Methods: Using stratified randomization, 281 Year 3 chiropractic students at 2 institutions were allocated into 1 of 3 educational interventions and served as active-control comparison groups: pain neuroscience education, chronic pain education, or patient-centered care.